Biomarkers/Genes Flashcards

1
Q

HLA-A3

A

haemochromatosis

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2
Q

HLA-B51

A

Behcet’s disease

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3
Q

HLA-B27

A

Arthritides

ankylosing spondylitis
reactive arthritis
acute anterior uveitis
psoriatic arthritis

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4
Q

HLA-DQ2/DQ8

A

coeliac disease

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5
Q

HLA-DR3

A

dermatitis herpetiformis
Sjogren’s syndrome
primary biliary cirrhosis

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6
Q

HLA-DR4

A

type 1 diabetes mellitus
rheumatoid arthritis - in particular the DRB1 gene (DRB104:01 and DRB104:04 hence the association with DR4)

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