Biomarkers/Genes Flashcards
1
Q
HLA-A3
A
haemochromatosis
2
Q
HLA-B51
A
Behcet’s disease
3
Q
HLA-B27
A
Arthritides
ankylosing spondylitis
reactive arthritis
acute anterior uveitis
psoriatic arthritis
4
Q
HLA-DQ2/DQ8
A
coeliac disease
5
Q
HLA-DR3
A
dermatitis herpetiformis
Sjogren’s syndrome
primary biliary cirrhosis
6
Q
HLA-DR4
A
type 1 diabetes mellitus
rheumatoid arthritis - in particular the DRB1 gene (DRB104:01 and DRB104:04 hence the association with DR4)