Biomarcadores Flashcards

1
Q

Câncer - ER e PR

A
  • Mama
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2
Q

Câncer - HER2

A
  • Mama
  • gástrico
  • esofágico
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3
Q

Câncer - CA125

A

(antígeno associado ao câncer 125)

  • Ovário
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4
Q

Câncer - PSA

A
  • Prsotático
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5
Q

Câncer - EGFR

A

Pulmonar (células não pequenas)

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6
Q

Câncer - KRAS

A
  • Colorretal
  • pulmonar
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7
Q

Câncer - BRAF

A
  • Colorretal
  • melanoma cutâneo
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8
Q

Câncer - ALK (quinase do linfoma anaplástico)

A
  • Pulmonar (células não
    pequenas);
  • Linfoma anaplásico de células grandes.
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9
Q

Câncer - CEA

A

(antígeno carcinoembriônico)

  • Colorretal
  • Mama
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10
Q

Câncer - AFP

A
  • Hepático
  • Células germinativas
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11
Q

Câncer - hCG

A

gonadotrofina coriônica humana

-Testicular
- Coriocarcinoma

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12
Q

Câncer - LDH

A

(lactato desidrogenase)

  • células germinativas
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13
Q

Câncer - CA 19-9

A

(antígeno associado ao câncer 19-9)

  • Pancreático
  • Vesicular
  • Ducto biliar
  • Gástrico
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14
Q

Câncer - CA15-3

A

(antígeno associado ao câncer 15-3)

  • Mama
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15
Q

Câncer - BRCA1 e BRCA2

A
  • Mama
  • Ovário
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16
Q

Câncer - APC

A
  • Colorretal
16
Q

Câncer - CA 27-29

A

(antígeno associado ao câncer 27-29)

  • Mama
17
Q

Câncer - B2M

A

beta-2microglobulina

Mieloma múltiplo
- leucemia linfoide crônica
- e alguns linfomas

18
Q

Câncer -BCR-ABL

A

cromossomo Philadelphia

  • Leucemia mieloide crônica
19
Q

Câncer - CD20

A
  • Linfoma não Hodgkin
20
Q

Câncer - CgA

A

(cromogranina A)

  • Neuroendócrino
21
Q

Câncer - c-KIT

A

(fator de crescimento de mastócito/células-tronco)

Estromal,
gastrointestinal
melanoma mucoso

22
Q

Cancer - NSE

A

(enolase neurônio-específica)

  • Neuroendócrino e carcinoide