Biology Vocabulary Flashcards
Evolution
Is change in the heritable characteristics of biological populations over successive generations/long period of time. These characteristics are the expressions of genes that are passed on from parent to offspring during reproduction. Different characteristics tend to exist within any given population as a result of mutation, genetic recombination and other sources of genetic variation. Evolution occurs when evolutionary processes such as natural selection (including sexual selection) and genetic drift act on this variation, resulting in certain characteristics becoming more common or rare within a population. It is this process of evolution that has given rise to biodiversity at every level of biological organisation, including the levels of species, individual organisms and molecules.
The scientific theory of evolution by natural selection was conceived by?
Charles Darwin and Alfred Russel Wallace in the mid-19th century in Darwin’s book: On the Origin of Species.
Gene
A heritable unit for transmission of biological traits.
A sequence of nucleotides in DNA or RNA that encodes the synthesis of a gene product, either RNA or protein.
Phenotype
pheno- ‘showing’, and ‘type’) the term used in genetics for the composite observable characteristics or traits of an organism.
The term covers the organism’s morphology or physical form & structure, its developmental processes, its biochemical and physiological properties, its behavior, and the products of behavior. An organism’s phenotype results from two basic factors: the expression of an organism’s genetic code (genotype) & the influence of environmental factors. Both factors may interact, further affecting phenotype.
Genotype
is an organism’s set of heritable genes that can be passed down from parents to offspring.
Polymorphism
is when there are two or more possibilities of a trait (phenotypes) on a gene in a population.
ie. more than 1 possible trait of jaguar’s skin coloring (dark morph or light morph).
Punnett square
is a square diagram used to predict the genotypes of a particular cross or breeding experiment. The diagram is a tabular summary of possible combinations of maternal alleles with paternal alleles. These tables can be used to examine the genotypical outcome probabilities of the offspring of a single trait (allele), or when crossing multiple traits from the parents. The Punnett square is a visual representation of Mendelian inheritance.
Allele
is a variant form of a gene. Some genes have a variety of different forms, which are located at the same position, or genetic locus, on a chromosome.
Humans are called diploid organisms because they have two alleles at each genetic locus, with one allele inherited from each parent. Each pair of alleles represents the genotype of a specific gene. Genotypes are described as homozygous if there are two identical alleles at a particular locus and as heterozygous if the two alleles differ. Alleles contribute to the organism’s phenotype, which is the outward appearance of the organism.
Some alleles are dominant or recessive. When an organism is heterozygous at a specific locus and carries one dominant and one recessive allele, the organism will express the dominant phenotype. Alleles can also refer to minor DNA sequence variations between alleles that do not necessarily influence the gene’s phenotype.
Evolution = Natural Selection
Genetic Variation over long periods of time
Chromosome
“Chromo” = “Colored” “Some” = “Body”
is a long DNA molecule with part or all of the genetic material of an organism. Most eukaryotic chromosomes include packaging proteins called histones which, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity. These chromosomes display a complex three-dimensional structure, which plays a significant role in transcriptional regulation.
Chromosomes are normally visible under a light microscope only during the metaphase of cell division (where all chromosomes are aligned in the center of the cell in their condensed form). Before this happens, each chromosome is duplicated (S phase), and both copies are joined by a centromere, resulting either in an X-shaped structure (pictured above), if the centromere is located equatorially, or a two-arm structure, if the centromere is located distally. The joined copies are now called sister chromatids. During metaphase the X-shaped structure is called a metaphase chromosome, which is highly condensed and thus easiest to distinguish and study. In animal cells, chromosomes reach their highest compaction level in anaphase during chromosome segregation.
Chromosomal recombination during meiosis and subsequent sexual reproduction play a significant role in genetic diversity. If these structures are manipulated incorrectly, through processes known as chromosomal instability and translocation, the cell may undergo mitotic catastrophe. Usually, this will make the cell initiate apoptosis leading to its own death, but sometimes mutations in the cell hamper this process and thus cause progression of cancer.
Eukaryote
“Eu” = “well”/“good” “Karyon” = “nut”/“kernel”
is an organism with complex cells, or a single cell with a complex structures. In these cells the genetic material is organized into chromosomes in the cell nucleus.
Eukaryotes Examples are:
Animals, plants, algae, fungi (mushrooms), single-celled protists (ie. amoeba & paramecium), Insects, & Humans are composed entirely of eukaryotic cells.
Prokaryote
“Pro” = “before” “Karyon” = “nut”/“kernel”
a microscopic single-celled organism that has neither a distinct nucleus with a membrane nor other specialized organelles. Prokaryotes include the bacteria and cyanobacteria.
Centromere
is a structure in a chromosome that holds together the two chromatids (the daughter strands of a replicated chromosome). The centromere is the point of attachment of the kinetochore, a structure to which the microtubules of the mitotic spindle become anchored.
Chromatin
is the material that makes up a chromosome that consists of DNA & protein. The major proteins in chromatin are proteins called histones. They act as packaging elements for the DNA.
Chromatid
is one of two identical halves of a replicated chromosome. During cell division, the chromosomes first replicate so that each daughter cell receives a complete set of chromosomes.
is one half of a duplicated chromosome. Before replication, one chromosome is composed of one DNA molecule. Following replication, each chromosome is composed of two DNA molecules; in other words, DNA replication itself increases the amount of DNA but does not increase the number of chromosomes
(Genotype) Fitness
is a measure of survival, mate-find, & reproductive success (how many offspring an organism leaves in the next generation, relative to others in the group). Natural selection can act on traits determined by alternative alleles of a single gene, or on polygenic traits (traits determined by many genes).
DNA
Deoxyribonucleic acid is a self-replicating molecule composed of two polynucleotide chains that coil around each other to form a double helix carrying genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and ribonucleic acid are nucleic acids.
DNA examples include: animals, plants, protists, archaea and bacteria. DNA is in each cell in the organism and tells cells what proteins to make.
DNA has a phosphate deoxyribose backbone
Genome
is an organism’s complete set of genetic instructions. Each genome contains all of the information needed to build that organism and allow it to grow and develop.
Nucleobase
There are a total of 5 nucleobases in DNA and RNA. These are cytosine, guanine, adenine (found in both DNA and RNA), thymine (found only in DNA), and uracil (found only in RNA). In DNA, adenine pairs with thymine, while cytosine pairs with guanine.
Nucleobases, also known as nitrogenous bases containing biological compounds that form nucleosides, which, in turn, are components of nucleotides, with all of these monomers constituting the basic building blocks of nucleic acids. The ability of nucleobases to form base pairs and to stack one upon another leads directly to long-chain helical structures such as ribonucleic acid (RNA) and deoxyribonucleic acid (DNA).
Five nucleobases—adenine (A), cytosine (C), guanine (G), thymine (T), and uracil (U)—are called primary or canonical. They function as the fundamental units of the genetic code, with the bases A, G, C, and T being found in DNA while A, G, C, and U are found in RNA.
Thymine and uracil are distinguished by merely the presence or absence of a methyl group on the fifth carbon (C5) of these heterocyclic six-membered rings.
Adenine and guanine have a fused-ring skeletal structure derived of purine, hence they are called purine bases. The purine nitrogenous bases are characterized by their single amino group (NH2), at the C6 carbon in adenine and C2 in guanine.
Similarly, the simple-ring structure of cytosine, uracil, and thymine is derived of pyrimidine, so those three bases are called the pyrimidine bases.
Each of the base pairs in a typical double-helix DNA comprises a purine and a pyrimidine: either an A paired with T (or) C paired with a G. These purine-pyrimidine pairs, which are called base complements, connect the two strands of the helix and are often compared to the rungs of a ladder. The pairing of purines and pyrimidines may result, in part, from dimensional constraints, as this combination enables a geometry of constant width for the DNA spiral helix. The A-T and C-G pairings function to form double or triple hydrogen bonds between the amine and carbonyl groups on the complementary bases.
Nucleobases such as adenine, guanine, xanthine, hypoxanthine, purine, 2,6-diaminopurine, and 6,8-diaminopurine may have formed in outer space as well as on earth.The origin of the term base reflects these compounds’ chemical properties in acid-base reactions, but those properties are not especially important for understanding most of the biological functions of nucleobases.
RNA
ribonucleic acid is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and DNA are nucleic acids which are present in all living cells.
RNA is single-stranded. An RNA strand has a backbone made of alternating sugar (ribose) and phosphate groups.
There are 4 types of RNA, each encoded by its own type of gene:
mRNA - Messenger RNA: Encodes amino acid sequence of a polypeptide.
tRNA - Transfer RNA: Brings amino acids to ribosomes during translation.
rRNA - Ribosomal RNA: With ribosomal proteins, makes up the ribosomes, the organelles that translate the mRNA.
snRNA - Small nuclear RNA: With proteins, forms complexes that are used in RNA processing in eukaryotes. (Not found in prokaryotes.)
mRNA
mRNA - Messenger RNA: Encodes amino acid sequence of a polypeptide.
tRNA
tRNA - Transfer RNA: Brings amino acids to ribosomes during translation.
rRNA
rRNA - Ribosomal RNA: With ribosomal proteins, makes up the ribosomes, the organelles that translate the mRNA.
snRNA
snRNA - Small nuclear RNA: With proteins, forms complexes that are used in RNA processing in eukaryotes. (Not found in prokaryotes.)