Biology Unit 1.1 Pathogens and disease Flashcards
What can a disease be defined as?
A condition that adversely affects and organisms physical or mental health. and shows recognizable symptoms. the term disease suggests a malfunction of the body.
What factors work in conjunction to cause a multifactorial disease?
- Poor diet- Unhealthy lifestyle- Being over weight- Being underweight- Smoking- drinking excessive amounts of alcohol
What are the nine categories of disease?
- Physical- Infectious- Non Infectious- Deficiency- Inherited- degenerative- Mental- Social- Self Inflicted
Physical Disease
Can cause temporary or permanent harm to the body. (Influenza)
Infectious Disease
Caused by specific pathogens and are infectious. (AIDS)
Non Infectious Disease
These are not spread by pathogens. (Cancer)
Deficiency Disease
These are caused by a lack of minerals and vitamins. (Jaundice)
Inherited Disease
These are inherited from one or both parents, often called genetic disorders. (Cystic fibrosis)
Degenerative Disease
Gradually causes damage to tissue and organs. (Arthritis)
Mental Disease
Surprisingly common and affect mental health. (Alzheimer’s)
Social Disease
Caused by our life style choices. Too many calories and little exercise. (Heart Disease, Diabetes)
What is a Pathogen?
- a pathogen is any organism that causes disease, they include fungi. virus and bacteria.
- Pathogens are usually microorganisms, Many permanently live in the body but cause us no harm. the ones that cause disease are pathogens
BacteriaDraw Diagran
- Bacteria are small single celled organisms- Bacteria cells are called prokaryotic cells and are much smaller than animal and plant cells
- Bacteria affect there host in many different ways but like viruses can kill cells.
- They compete for vital nutrients. Bacteria invade host cells but do not require a host cell In order to reproduce.
- There are vast amounts of bacteria in our body, most are either beneficial or not harmful to us
Transmission Social Interaction?
- Caused by shaking hands, coughing, sneezing, and kissing.
- (Influenza, tuberculosis and the common cold are spread this way)
Transmission Food and Water?
- Drinking or eating things which are contaminated with pathogens
.- Food poisoning (E.coli, salmonella and botulism)- Water borne (Cryptosporidium and Cholera)
Transmission Self inflicted disease
Caused by smoking and drinking excessively. (Lung cancer, Liver disease)
Transmission Sexual Contact?
- STI’s (HIV, syphilis, Chlamydia)
Transmission Cross Species infection?
- Animal bites or handling faeces (Rabies and Toxoplasmosis from animals)
Transmission Vector Born Infections?
- Insects (Mosquitoes) carrying pathogens without infection pass the disease on to humans in their bite. (Malaria)
Transmission Contact with surfaces?
- Fungal skin infections can be transmitted from person to person via floors, footwear and shower stalls. (Athletes foot)
Fungi Draw Diagram
- fungi originate from the same famil as mushrooms and toadstools.
- Pathogenic And parasitic fungi are unicellular, their cells are eukaryotic like plant and animal cells but there cellular make up is different
.- fungal I reactions usually affect the skin however they can affect us internally if I inhaled or ingested.
Micro organisms as pathogens
For a micro organism to be considered as a pathogen it must
- Gain entry to the host
- Colonizes the tissue of the host- Resist the defenses of the hose- Cause damage to the hosts tissues
Biology and Disease unit info
Looks at how some diseases are caused by micro organisms and some are caused by our lifestyle. It explains how to interpret data about disease and shows why this is essential in determining the risk posed by certain aspects of our behavior
Infection
An infection occurs when a pathogen colonises a hosts tissue.
Transmission
When a pathogen is transferred from one host to another.
Interface
Surface or boundary linking two systems.
What are the three main interfaces pathogens enter out body
The gas exchange system including tuberculosis and bronchitisThe digestive system, food and water carry pathogens, cholera, typhoid and dysentery enter the body this way.The skin can be penetrated through cuts and abrasion
What defences has the body got against invasion from pathogens
A mucous layer that covers exchange surface and forms a thick sticky barrier that is difficult to penetrateThe production of enzymes that break down pathogensThe production of stomach acid that kill microorganisms.
Why are the digestive respiratory systems usually the site of entry of pathogens?
These systems have evolved to allow the exchange of materials from the internal and external environments, The Body linings at these points are thin, have mucus, are sticky, have large surface areas and lots of blood vessels allowing for entry of molecules but also making them vulnerable to pathogen invasion.
Patho Pathology Pathogenesis Pathophysiology
Patho - DiseasePathology - The study of disease
Pathogenesis - the pattern or development of the disease
Pathophysiology - the study of the mechanism, how it works when it infects.
How to pathogens cause disease?
Producing toxins
Damaging host tissue
Most bacterial pathogens produce toxins that destroy the cell. The Cholera bacterium produces a toxin that results in water loss from the lining of the intestines.
The sheer number of pathogens prevent tissues functioning properly. Viruses inhibit the synthesis of DNA and RNA and proteins by the host cells.
Many pathogens break down the membranes.
How to pathogens cause disease?Damaging host tissues
sheer numbers of pathogens Prevent tissue from functioning properly, viruses inhibit they synthesis of DNA and RNA and proteins by the host cells. Many pathogens break down the host cells
What is a micro organisms
- General term is single celled organism to small to be seen without a microscope usually bacteria. Most are benign or beneficial/
What is a virus? diagram
A virus is an acellular organism or living organism with no cell.
- 1 % the size of a bacterium cell
- Contain DNA and RNA
- Proflific on our planet
- needs a host in order to grow, once inside a cell they reproduce excreting cytopathic chemicals that harm cellular tissue and eventually destroy the cell
Signs
Objective abnormality in the body
Symptoms
subjective abnormality in the body
syndrome
Downsyndrome - the collection of signs and symptoms
Ethology
Study of all factors that cause a disease
idiopathic
Diseases with unknown causes - cancer
Acute
Signs and symptoms occur suddenly and disappear in time - common cold
Chronic
Disease develops gradually and lasts or a long time - chronic back pain
Aids
HIV
Acquired immune deficiency syndrome
Human Immune deficiency virus
Endemic
Disease quietly maintained in a country
Epedemic
A disease that rapidly spreads to many people in the same area
Pandemic
Worldwide spread of disease
Diffusion
The exchange of substances between cells and environment