Biology Lecture Week 6 - Biological Materials Flashcards

1
Q

Bone contains the following …

A
  • 25-30% water
  • Collagen (30% dry weight). Gives resistance to tensile loading, ductility (flexibility) and toughness (resistance to shock loading
  • Minerals (about 70% of dry weight). Mainly calcium phosphate/carbonate. These resist compression, and provide rigidity
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2
Q

Bone is capable of withstanding loads …

A

Six times those experienced in normal life

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3
Q

Define what Osteocytes are …

A

A specialised form of connective tissue which are light, in a collagen matrix and packed with minerals

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4
Q

What are the two types of bone ?

A
  1. Cortical
  2. Trabecular

The combined strength to weight ratio is greater when combined than in the individual parts

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5
Q

Compressive and tensile forces act on bone, which type of bone is better at resisting these forces ?

A

Cortical bone as trabecular bone is much weaker in resisting either type of force

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6
Q

What are the different types of [fracture patterns] and their {load type} ?

A

1: [Diaphyseal impaction] - {Axial Compression}
2: [Transverse] - {Bending}
3: [Spiral] - {Torsion}
4: [Oblique transverse and butterfly] - {Axial compression and bending}
5: [Oblique] - {Axial Compression, bending, torsion}

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7
Q

Define a transverse fracture …

A
  • Bending Load
  • Cortical bone weaker in tension than compression so bone under tension fails first
  • Failure mechanism is break propagation perpendicular to bone’s long axis, from surface layer inwards
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8
Q

Describe what Cartilage is …

A
  • Cells are widely separated within a fibrous, organic matrix which may:
    • appear (but isn’t) structureless as in rigid hyaline cartilage
    • contain more connective tissue fibres in the matrix (eg. fibrocartilage)
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9
Q

What does Cartilage consist of (genetic make-up)

A
  • Cells (chondrocytes) account for less than 10% of tissue volume
  • the organic matrix consists of collagen fibrils (10-30% net weight) within a proteoglycans solution (3-10%) net weight
  • Remainder of tissue (60-87% is made up of water, inorganic salts and small quantities of matrix proteins, glycoproteins and lipids
  • its mechanical properties are dependant on the direction of loading (anisotropic)
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10
Q

what are Cartilage’s Biomechanical Properties

A
  • Cartilage shows typical viscoelastic behaviour:
    • loading leads to rapid initial deformation followed by more gradual increase
    • returns to initial shape on load removal (hysteresis)
    • prolonged standing causes creep of intervertebral discs (hence shortening of the body’s overall height
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11
Q

What leads to Articular Cartilage Injuries …

A
  • Articular cartilage is capable of deformation; decreases stress on the joints by increasing load-bearing area
  • Avascular and tends to have few nerve endings, meaning it shows little external symptoms and repairs poorly
  • Overuse injuries cause cartilage to wear away, leading to osteoarthritis
  • High impact loads lead to swelling of cartilage; if sever enough may fracture
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12
Q

What are Tendons ?

A

Tough cords of closely packed collagen fibres

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13
Q

What are Aponeuroses ?

A

Sheet like tendons

Attach muscles to bones and transmit tensile loads so that movement can occur

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14
Q

What are Deep facia ?

A

Occur between muscles, enveloping individual muscles and binding them in groups

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15
Q

What is Intermuscular Septa ?

A

Separates muscle groups passing from the deep fascia to the bone

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16
Q

What are Ligaments ?

A

Like tendons but contain some elastic fibre (elastin)

17
Q

What are Ligamentous joint capsules ?

A

connect bone to bone, guide joint motion, enhance mechanical stability and prevent excessive motion

18
Q

What is the ultimate failure strain of tendons ?

A

between 8-10% (Herzog and Loitz, 1994)

19
Q

Tendons have limited viscoelastic behaviour with only __ to __ hysteresis ? (Herzog and Loitz, 1994)

A

2.5 to 20%

20
Q

Tendons are considered the main site for …

A

High energy return during elastic recoil in the muscle-tendon unit (alexander, 2002)

21
Q

The achilles tendon …

A

is an important site for energy storage before jumping in athletes. Basket ballers and high jumpers tend to have short, powerful calf muscles and long Achilles tendons

22
Q

Facts about ligaments …

A
  1. designed to best cope with tensile forces
  2. most everyday activities occur in the high deformation/ low force to region of the stress strain curve allowing easy movement
  3. stiffness increases with force applied preventing bones from pulling apart
  4. ligaments have mechanoreceptors which may initiate tension in nearby muscles in order to assist in maintaining joint stability eg rapid knee extension
23
Q

How do ligament sprains occur ?

A

excessive joint motion, most not severe

24
Q

Direct blows to ligaments can cause ?

A

stretching and permanent deformation

25
Q

“failure often due to bending and torsional loads applied to distal limb, as in tackle, and depends on load rate” what 3 other ligament injuries occur due to load rates ?

A

1 - mid substance tear at fast load rates
2 - bony avulsion at low load rates, mostly in young athletes
3 - separation of bone-ligament interface - rare because of its strength

26
Q

What are the effects of tears in the ligaments ?

A
  • loss of stability, joint misalignment, abnormal contact pressure, loss of proprioception
27
Q

Muscle stiffness is related to …

A

the force produced un relation to its length

28
Q

Maximal muscle stiffness is encountered during …

A

eccentric contraction, up to 200 times that in concentric and is probably under reflex control

29
Q

Muscle and tendon should be considered a …

A

single unit where neither connective tissue acts independently of the other