Biology - Gene Expression (4) Flashcards
What is rRNA?
The ribosome is made up of rRNA and protein. stands for ribosomal RNA.
Redundancy of genetic code
There are 64 possible codons, but only 20 amino acids that code for it. There are more amino acids that code for a codon, so the codons don’t exactly matter. USE EXAMPLE
What is a metabolic pathway?
A metabolic pathway is a series of enzyme-controlled, chemical
reactions where the product of one reaction is the substrate for the next.
Where does transcription occur?
The nucleus of the cell. It then leaves through the nuclear pore
Where does translation occur?
The cytoplasm of the cell. It connected to a ribosome.
When drawing DNA, etc.
Left is 5’ - 3’ and right is opposite and upside down.
Coding/template strand
Coding - identical to mRNA
Template - is used to code for mRNA
Why can’t DNA be converted to polypeptide chains?
- It’s too long. It can’t leave the nuclear pore and it takes a long time as only 1 protein can be made at a time.
- Risks of damage. It might get destroyed by enzymes
Secondary structure protein folding
Alpha-helix and beta-pleated sheets. Joined by hydrogen bonding
Primary structure protein folding
Polypeptide chain. Is the resultant of translation
Tertiary structure protein folding
Alpha-helix and beta-pleated sheets. Joined together by disulphide bonds
Quarternary structure
Multiple polypeptide chains. Non-covalent bonds. Complex protein
Environmental factor/mutagen
EV: Factor that doesn’t change the genotype, but affects the expression of the phenotype
Mutagen: Causes a mutation
Hydrogen bonds
AT - 2
CG - 3
Amino acid
Building blocks of proteins