Biology Anatomy Flashcards
5’ cap
a methylated guanine nucleotide added to the 5’ end of eukaryotic mRNA. The cap is necessary to initiate translation of mRNA
a band
The band of the sarcomere that extends the full
length of the thick filament. The A band includes
regions of thick and thin filament overlap, as well as a region of thick filament only. A bands alternate
with I bands to give skeletal and cardiac muscle a
striated apperance. The A band does not shorten
during muscle contraction.
absolute refractory period
A period of time following an action potential during
which no additional action potential can be evoked
regardless of the level of stimulation. (usually
because Na+ channel closed whle K+ efflux)
accessory glands
The three glands in the male reproductive system
that reproduce semen: the seminal vesicles, the
prostate, and the
accessory organs
(1) In the GI tract, organs that play a role in
digestion but not directly part of the alimentary
canal. These include the liver, the gallbladder, the
pancreas, adn the salivary glands.
acetylcholine ACh
The neurotransmitter used throughout the
parasympathetic nervous system as well as the
neuromuscular junction.
acetlycholinesterase (AChE)
The enzyme that breaks down acetylcholine in the
synaptic cleft.
Acetyl-CoA
The first substrate in the Krebs cycle, produced
primarily from the oxidation of pyruvate by the
pyruvate dehydrogenase complex, however
acetyl-CoA is also produced during fatty acid
oxidation and protein catabolism.
acid hydrolases
Enzymes that degrade various macromolecules and that require an acidic pH to function properly. Acid hydrolases are found within the lysosomes of cells.
acinar cells
Cells that make up exocrine glands, and that secrete their products into ducts. For example, in the pancreas, acinar cells secrete digestive enzyme; in the salivary glands, acinar cells secrete saliva.
acrosome
A region at the head of a sperm cell that contains
digestive enzyems which, when released during the acrosome reaction, can facilitate penetration of the corona radiata of the egg, and subsequently,
fertilization
actin
A contractile protein. In skeletal and cardiac muscle, actin polymerizes (along with other proteins) to form the thin filaments. Actin is involved in many contractile activities, such as cyotkinesis, pseudopod formation, and muscle contraction.
action potential
A localized change in a neruon’s or musce cell’s
membrane potential that can propogate itself away
from its point of origin. Action potentials are an
all-or-none process mediated by the opening of
voltage-gated Na+ and K+ channels when the
membrane is brought to the threshold potential;
opening of the Na+ channels causes a characteristic
depolarization, while opening of the K+ channels
repolarizes the membrane.
activation energy (Ea)
The amount of energy required to produce the
transition state of a chemical reaction. If the
activation energy for a reaction is very high, the
reaction occurs very slowly. Enzymes (and other
catalysts) increase reaction rates by reducing
activation energy.
active site
The 3D site of an enzyme where substrates
(reactants) bind and a chemical reaction is
facilitated.
active transport
The movement of molecules through the plasma
membrane against their concentration gradients.
Active transport requires input of cellular energy,
often in the form of ATP. An example is the Na+/K+
ATPase in the plasma membrane of all cells.
adenine
One of the four aromatic bases found in DNA and
RNA; also a component of ATP, NADH, and FADH2. Adenine is apurine; it pairs with thymine (in DNA) and with uracil (in RNA)
adenohypophis
anterior pituitary gland