Biology Flashcards

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1
Q

synapses can be both…

A

chemical and electrical

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2
Q

inhibitory synapses cause the release of….

A

neurotransmitters that cause an influx of negative ions or an efflux of positive ions leading to hyper polarization, inhibiting the action potential

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3
Q
A
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4
Q

Multiple sclerosis is a

A

neurodegenerative disease in which immune cells attack the myelin sheaths surrounding axons in the central nervous system (CNS).

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5
Q

Huntington’s disease

A

is an autosomal dominant genetic neurodegenerative disease in which neuronal loss occurs in extensive regions of the brain, including the basal ganglia.

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6
Q

in the CNS, gray matter is composed of

A

neuronal cell bodies

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7
Q

in the CNS, white matter is composed of

A

axons that allow long-distance communication between neurons

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8
Q

In the white matter of the spinal cord, afferent axons carry

A

sensory information to the brain

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9
Q

in the white matter of the spinal cord, efferent axons carry

A

motor commands to the body.

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10
Q

the glial cells of the CNS are

A

oligodendrocytes, astrocytes and ependymal cells, microglia

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11
Q

oligodendrocytes

A

form myelin sheaths around axons to reduce ion leakage and increase action potential propagation speed

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12
Q

astrocytes

A

support, blood-brain barrier, interstitial space

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13
Q

ependymal cells

A

epithelial cells that line the compartments of the CNS and secrete CSF

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14
Q

Glial cells in the PNS

A

Schwann cells (myelin)

satellite cells (structural support + nutrients to near cell bodies)

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15
Q

microghlia

A

macrophages of the CNS

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16
Q

the blood brain-barrier is composed of

A

endothelial cells held together by tight junctions to regulate transport through four routes

17
Q

route 1 to BBB

A

paracellular transport (between cells) is limited for hydrophilic molculces

18
Q

route 2 to BB

A

transcellular route will allow small, lipophilic molecules in by passive transport (diffusion), including

non polar gases (e..g diatomic, CO2)

steroid hormones

19
Q

route 3 to BBB

A

carrier-mediated transport which uses facilitated diffusion and active transport allows large or hydrophilic molecules like amino acids or nucleosides

20
Q

route 4 to BBB

A

through endocytosis to transport molecules in bulk

21
Q

aldosterone

A

secreted by the adrenal cortex, increases na absorption to increase water retention in the kidneys to increase blood pressur/volume

22
Q

norepinephrine and epinerine from the adrenal medulla

A

mobilize body under extreme stress including changes to blood vessel diameter

23
Q

vasoconstriction

A

higher BP but lower nutrients delivered to tissues

24
Q

vasoconstriction

A

lower BP but more nutrients delivered to tissues

25
Q

adrenal cortex makes

A

steroid hormonesad

26
Q

adrenal medulla

A

makes peptide hormones

27
Q

an endogenous substance is

A

one that is produced in the body e.g. endogenous cortisol

28
Q

myelin sheath has nodes of ranvier where charges can leak across the swath and back into the extracellular space.

A
29
Q

when AP flows down from node to node

A

saltatory conduction

30
Q
A