Biology Flashcards

Biology NMAT

1
Q

action or process of examining of something
such as phenomena or problem

A

Observation

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2
Q

a possible or specific explanation or
phenomenon; scientific guess

A

Hypothesis

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3
Q

a statement about whether a theory hypothesis
should be accepted, rejected, or modified based on tests of the
prediction derived from it.

A

Conclusion

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4
Q

A research method in which the researcher
manipulates one or more independent variables to observe
their effect on a dependent variable, while controlling for other
factors.

A

Experiment

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5
Q

A research technique that involves
systematically analyzing and interpreting the content of various
forms of communication, such as written or verbal language,
images, or media, to identify patterns or themes.

A

Content Analysis

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6
Q

A research method that involves analyzing
historical records, documents, or data to study past events or
behaviors, and to draw conclusions or insights about the
present or future

A

Archival Research

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7
Q

All organisms share the ff. common characteristics - made up of

A

basic unit of life-cell

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8
Q

includes the whole Earth and all its living
organisms

A

Biosphere

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9
Q

a community and its physical_
environment

A

Ecosystem

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10
Q

the population of all species occupying
the same area

A

Community

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11
Q

group of individuals belonging to the
same species occupying a given area at the same
time

A

Population

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12
Q

an individual composed of
specialized, interdependent cells arrayed in tissues,
organs and often organ system

A

Multicellular Organism

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13
Q

two or more organs interacting
chemically, physically or both

A

Organ System

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14
Q

structural unit in which tissues are combined
in specific amounts and patterns that allow them to
perform a common task

A

Organ

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15
Q

group of cells with the s a m e specialized
function

A

Tissues

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16
Q

smallest living unit, may be
unicellular/multicellular

A

Cell

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17
Q

sacs other compartments that separates
activities inside the cell

A

Organelle

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18
Q

three or more chains of the same
molecules such as proteins, carbohydrates, fats &
nucleic acids

A

Biomolecule

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19
Q

two or more atoms of the same or different
elements bonded together

A

Molecule

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20
Q

smallest non-living unit

A

Atom

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21
Q

are small, circular pieces of DNA that exist separately from the
chromosomal DNA in bacterial and archaeal cells

A

Plasmids

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22
Q

They are often referred to as extrachromosomal elements and
can carry genes that confer some sort of advantage to the
host cell, such as antibiotic resistance, virulence factors, or
metabolic capabilities

A

Plasmids

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23
Q

can replicate independently of the host cell’s
genome and can be transferred between cells through
conjugation, transduction, or transformation

A

Plasmids

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24
Q

type of plasmid that is responsible for
bacterial conjugation, carrying the genes necessary for the
production of the conjugation pilus and the relaxase enzyme

A

F plasmid

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25
This plasmid plays a crucial role in the acquisition and transfer of new traits among bacteria, contributing to the evolution and adaptation of bacterial populations
F plasmid
26
A bacteriophage that displays lysogenic life cycle in contrast to virulent phage that does not have the ability to display lysogeny
Temperate phage
27
A bacteriophage, that infects the bacterial species Escherichia coli
Lambda phase
28
just any plasmid containing an antibiotic (R)sistance gene
R plasmid
29
are extrachromosomal pieces of DNA that exist separately from the chromosomal DNA in bacterial cells. They can carry genes that confer some sort of advantage to the host cell, such as antibiotic resistance, virulence factors, or metabolic capabilities.
Plasmids
30
have been widely used as tools in genetic engineering and biotechnology, as they can be manipulated to carry foreign DNA and used to express genes of interest in a host cell
Plasmids
31
The plasmid DNA and target DNA containing the gene of interest are isolated from the host organism using standard DNA extraction methods
Isolation of Plasmid DNA and Target DNA
32
The plasmid and target DNA are cut using a restriction enzyme. The restriction enzyme used should cut the plasmid and target DNA at the same site to create matching sticky ends
Cutting the Plasmid and Target DNA
33
The plasmid and target DNA fragments are mixed with DNA ligase, which catalyzes the formation of phosphodiester bonds between the matching sticky ends of the plasmid and target DNA fragments.
Ligation of DNA Fragments
34
The recombinant plasmid is then inserted into the host organism using transformation techniques such as heat shock, electroporation, or chemical transformation.
Transformation
35
The transformed cells are screened for the presence of the recombinant plasmid using methods such as PCR or DNA sequencing
Screening
36
Once the presence of the recombinant plasmid is confirmed, the host organism can be grown in large quantities to produce the gene of interest
Mass Production
37
CELLULAR BASIS OF LIFE
Carbohydrates, Lipids, Proteins, DNA
38
consist of sugar (monosaccharides) and polymers of sugars (disaccharides and polysaccharides)
Carbohydrates
39
The most important monosaccharide
glucose
40
are key metabolites used in the synthesis of other organic molecules, as well as the substrates of glycolysis and the products of photosynthesis
Sugars
41
Glucose-Fructose
Sucrose
42
Glucose-Galactose
Lactose
43
Glucose-Glucose
Maltose
44
Used by plants to store energy
Starch
45
used by animals to store energy
Glycogen
46
used by plants to form rigid walls around cells
glucose
47
used by some animals to form an external skeleton
Chitin
48
are a diverse group of organic molecules that are characterized by their hydrophobic nature, meaning that they are insoluble in water
lipids
49
play many important roles in living organisms, including serving as a source of energy, a component of cell membranes, and signaling molecules
lipids
50
are composed of building blocks called fatty acids and glycerol. Fatty acids are long-chain hydrocarbons with a carboxyl group (-COOH) at one end. Glycerol is a three-carbon alcohol molecule that has three hydroxyl (-OH) groups.
lipids
51
Linked together by ester bonds through dehydration reactions to form triglycerides
fatty acids and glycerol
52
the main type of fat in the body
triglycerides
53
are stored in adipose tissue as a long-term energy reserve that can be broken down when needed to provide energy for the body
Triglycerides
54
Types of Triglycerides:
1. Saturated fatty acids 2. Unsaturated fatty acids
55
Composed of a glycerol molecule, two fatty acid chains, and a phosphate group. The phosphate group has a polar head and a nonpolar tail, which allows it to form a bilayer in cell membranes, creating a barrier between the cell and its environment
Phospholipids
56
Characterized by a four-ring structure
steroids
57
is a well-known steroid that is an important component of cell membranes and is also a precursor to important hormones like testosterone and estrogen
cholesterol
58
FUNCTIONS OF LIPIDS
1. Energy Storage 2. Structural Components of Cell Membranes 3. Signaling Molecules 4. Insulation and Protection
59
polymers made up of different combinations of 20 commonly occurring amino acid monomers
Proteins
60
have a wide variety of functions, including structural components of cells and tissues, transport proteins in the cell’s membranes, and as catalysts called enzymes
Proteins
61
Connected by a linear sequence through the formation of peptide bonds by dehydration synthesis
Proteins
62
Proteins have four levels of physical structure
1. Primary Structure 2. Secondary structure 3. Tertiary Structure 4. Quaternary Structure
63
refers to the specific linear sequence of amino acids in a polypeptide.
Primary Structure
64
the initial folding patterns of certain lengths of the polypeptide chain, such as alpha helices and beta pleated sheets
Secondary structure
65
refers to the overall shape in which a polypeptide eventually folds
Tertiary Structure
66
arises from the association of two or more folded polypeptides to form a multi-subunit protein
Quaternary Structure
67
Protein Synthesis
DNA –transcription- mRNA –translation- Protein
68
transfers specific amino acids to growing polypeptide chain during translation
tRNA
69
conveys genetic information from DNA to the ribosome and is encoded in a sequence of nucleotides
mRNA
70
ribonucleic acid found in the nucleolus of the cell
nRNA
71
o act as a catalyst o globular proteins o Lower energy of activation and increase rate of reaction o Are not consumed or altered by reaction o Do not alter the equilibrium
Enzyme
72
Enzyme inhibition
1. Competitive inhibitors 2. Noncompetitive inhibitors 3. Allosteric inhibitor
73
compete with substrate by binding to active site
Competitive inhibitors
74
bind to enzyme in area other than active site
Noncompetitive inhibitors
75
bind to enzyme and change configuration of enzyme
Allosteric inhibitor
76
made from monomers called nucleotides
Nucleic Acids (DNA and RNA)
77
A 5 carbon sugar —either deoxyribose (in DNA) or ribose (in RNA). A phosphate group —present on a nucleotide
Nucleotide
78
is a molecule that contains the genetic instructions for the development and function of all living organisms
DNA Deoxyribonucleic Acid)
79
are two essential processes that have revolutionized our understanding of genetics and molecular biology.
DNA sequencing and protein synthesis
80
is the process of determining the order of nucleotides (A, C, G, and T) in a DNA molecule
DNA sequencing
81
a type of DNa sequencing, which was developed in the 1970s and is still widely used today
Sanger sequencing method
82
involves using DNA polymerase to synthesize new DNA strands, with the addition of dideoxynucleotides (ddNTPs) that terminate the DNA strand at specific positions
Sanger sequencing method
83
is the process by which the genetic information in DNA is used to synthesize proteins.
Protein synthesis
84
Protein synthesis involves two main stages
transcription and translation
85
DNA Enzymes
1. Permease 2. DNA Ligase 3. Endonucleases 4. tRNA Synthetase
86
An enzyme that facilitates the transport of molecules across biological membranes. Membranes are selectively permeable barriers that separate the interior of cells from their external environment
Permease
87
An enzyme that catalyzes the formation of phosphodiester bonds between the 3' hydroxyl group of one DNA fragment and the 5' phosphate group of another DNA fragment
DNA Ligase
88
and is essential for the repair of damaged DNA, the replication of DNA, and the recombination of DNA fragments
DNA Ligation
89
An enzymes that cleave DNA at specific sites. They are used in DNA repair, recombination, and the defense against foreign DNA such as viruses.
Endonucleases
90
An enzyme that catalyzes the attachment of amino acids to tRNA molecules during protein synthesis
tRNA Synthetase
91
are small RNA molecules that act as adapters between the mRNA code and the amino acids that make up proteins
tRNA
92
contains all DNA in animal cell
Nucleus
93
double phospholipid bilayer that surrounds nucleus and has pores for RNA to move out
Nuclear envelope or membrane
94
where rRNA is transcribed and the subunits of ribosomes are assembled
Nucleolus
95
flattened sacs with many ribosomes and synthesizes proteins
Rough endoplasmic reticulum
96
modifies and packages proteins for use in other parts of the cell
Golgi complex
97
contain hydrolytic enzymes that digest substances
Lysosomes
98
tubular, lipid synthesis and detoxification of drugs
Smooth endoplasmic reticulum
99
vesicles in cytosol involved in production and breakdown of hydrogen peroxide
Peroxisomes
100
make proteins
Ribosome
101
part of nucleus and distinct during replication
Chromosomes
102
a network of filaments that determine the structure and motility of the cell
Cytoskeleton
103
larger than microfilaments; rigid hollow tubes made from tubulin involved in flagella and cilia construction and spindle apparatus
Microtubules
104
squeeze membrane together in phagocytosis and cytokinesis the contractile force in microvilli and muscle
Microfilaments
105
tail of sperm so it can move
Flagella
106
are found only in fallopian tubes and respiratory tract of humans
Cilia
107
involved in cell division. Microtubules grow from it.
Centrosome
108
function in production of flagella and cilia, but not for microtubule production
Centrioles
109
plays a critical role in the synthesis, modification, and transport of proteins,The binding of ribosomes to the outer surface allows for the proper folding and modification of secretory and membrane proteins
Endoplasmic reticulum
110
separates internal environment from external environment and allows substances to be transported in and out of the cell
Plasma Membrane
111
the plasma membrane is selectively permeable, meaning that it allows some substances to pass through it, but not others
Selective Permeability
112
It is a direct consequence of the membrane structure
the Fluid Mosaic Model
113
Functions of membrane proteins include:
1. Transport, enzymatic activity 2. signal transduction 3. cell communication
114
Cell Membrane Transport : Against a gradient
Active Cell Membrane Transport
115
Cell Membrane Transport : Uphill (pump)
Active Cell Membrane Transport
116
Cell Membrane Transport : ATP Utilization
Active Cell Membrane Transport
117
Cell Membrane Transport : Usually with carries
Active Cell Membrane Transport
118
Cell Membrane Transport : specific
Active Cell Membrane Transport
119
Cell Membrane Transport : Undergoes inhibition
Active Cell Membrane Transport
120
Cell Membrane Transport : Saturation
Active Cell Membrane Transport
121
Cell Membrane Transport : Undirectional
Active Cell Membrane Transport
122
Cell Membrane Transport : Hydrophilic --> Carrier proteins --> ATP is used
Active Cell Membrane Transport
123
Cell Membrane Transport : (-) lipid bilayer
Active Cell Membrane Transport
124
Cell Membrane Transport : Living cells
Active Cell Membrane Transport
125
Cell Membrane Transport : Transcellular
Active Cell Membrane Transport
126
Cell Membrane Transport : Along a gradient
Passive Cell Membrane Transport
127
Cell Membrane Transport : Downhill
Passive Cell Membrane Transport
128
Cell Membrane Transport : No ATP consumption
Passive Cell Membrane Transport
129
Cell Membrane Transport : Usually no carries
Passive Cell Membrane Transport
130
Cell Membrane Transport : Specific/Non specific
Passive Cell Membrane Transport
131
Cell Membrane Transport : No inhibition
Passive Cell Membrane Transport
132
Cell Membrane Transport : Equilibrium
Passive Cell Membrane Transport
133
Cell Membrane Transport : Bidirectional
Passive Cell Membrane Transport
134
Cell Membrane Transport : Water and Hydrophilic ---> Protein Channels (gated/non gated) no ATP used
Passive Cell Membrane Transport
135
Cell Membrane Transport : Lipophilic --> Lipid bilayer
Passive Cell Membrane Transport
136
Cell Membrane Transport : Living and non-living cells
Passive Cell Membrane Transport
137
Cell Membrane Transport : Transcellular and Paracellular
Passive Cell Membrane Transport
138
In diffusion, a substance moves down its concentration gradient from an area of higher concentration to an area of lower concentration
Passive Transport
139
transport proteins move charged molecules (e.g., potassium ions) and larger molecules (e.g., glucose) into and out of the cell.
facilitated diffusion
140
glucose has been broken down completely to CO2 and H2O and produces 10 coenzyme molecules (8 NADH & 2 FADH2)
Kreb’s cycle
141
an electrochemical gradient of hydrogen ions (protons) across the thylakoid membranes that undergoes redox reactions in a series.
ETC
142
glycolysis and reduction of pyruvate producing ethanol or lactic acid and NAD+
Fermentation
143
absence of O2 result in 2ATP/mol of glucose
Anaerobic Respiration
144
presence of O2 results in net 36ATP/mol of glucose
Aerobic Respiration
145
refers to the complex network of biochemical processes that occur within living organisms
Metabolism
146
Types of Metabolism
Catabolic and Anabolic metabolism
147
Process of breaking down complex molecules into simpler ones. In this process, energy is released, which can be stored and used later
Catabolic Metabolism
148
is responsible for the breakdown of food into smaller molecules, such as glucose, which can then be used to produce energy in the form of ATP
Catabolic Metabolism
149
Process of building complex molecules from simpler ones. In this process, energy is required to create bonds between molecules, and these bonds are stored as potential energy
Anabolic Metabolism
150
is responsible for the synthesis of new molecules such as proteins, nucleic acids, and carbohydrates. The process of photosynthesis, which involves the conversion of carbon dioxide and water into glucose and oxygen
Anabolic Metabolism
151
reactions require energy input to proceed. In other words, the potential energy of the products is higher than that of the reactants, are non-spontaneous and require an input of energy to occur ex: the synthesis of glucose during photosynthesis, as energy is required to create bonds between molecules
Endergonic Metabolism
152
reactions release energy as a product. In other words, the potential energy of the reactants is higher than that of the products, are spontaneous and do not require energy input to proceed. The breakdown of glucose through cellular respiration
Exergonic Metabolism
153
Process by which cells produce energy in the form of ATP molecules from the breakdown of glucose and other organic molecules
CELLULAR RESPIRATION
154
The process of cellular respiration can be divided into three main stages
1. Glycolysis 2. Krebs Cycle 3. Oxidative Phosphorylation
155
is the first stage of cellular respiration and takes place in the cytoplasm of the cell, glucose is converted into two molecules of pyruvate, producing a net gain of two ATP molecules
Glycolysis
156
also known as the citric acid cycle or the tricarboxylic acid cycle, takes place in the mitochondria of the cell
Krebs cycle
157
separation of the cellular cytoplasm due to constriction of microfilaments about the center of the cell
Cytokinesis
158
is the first phase of the cell cycle and is characterized by cell growth and preparation for DNA replication in the S phase
G1 phase
159
nuclear division with genetic change
Mitosis
160
condensation of chromatin into chromosomes; Centrioles move to opposite ends of cell; Nucleolus and nucleus disappear; Spindle apparatus forms
Prophase
161
chromosome align at equator
Metaphase
162
sister chromatids split and move toward opposite ends of cell
Anaphase
163
nuclear membrane reforms the nucleolus; Result: 2 identical daughter cells
Telophase
164
double nuclear division which produces 4 haploid gametes
Meiosis
165
homologous chromosomes line up alongside each other, matching their genes exactly. May exchange sequences of DNA (crossing over)
Prophase I
166
homologs move to metaphase plate, do not separate
Metaphase I
167
homologs separate
Anaphase I
168
Nuclear membrane may or may not form. If cytokinesis occurs the cells are haploid with 23 chromosomes
Telophase I
169
produces two daughter cells that are genetically identical to the parent cell and have the same number of chromosomes (i.e., diploid)
Mitosis
170
produces four daughter cells that are genetically unique from the parent cell and have half the number of chromosomes (i.e., haploid).
Meiosis
171
functional unit chemically composed of DNA
Gene
172
sum total of all the genes present in a n individual
Genome
173
any member of a given pair of genes o if the alleles are identical then the condition is said to be homozygous and the individual is a homozygote; o if the alleles are non-identical, then the condition is said to be heterozygous and the individual is a heterozygote.
Allele
174
genetic composition of an individual
Genotype
175
external appearance of an individual
Phenotype
176
involves single pair of contrasting genes
Monohybrid Cross
177
involves 2 pairs of contrasting genes
Dihybrid Cross
178
involves three or more pairs of contrasting genes
Polyhybrid Cross
179
parents of a cross
Parental Generation (P)
180
offsprings of a cross
Filial Generation (F)
181
first filial generation (children)
F1
182
second filial generation (grandchildren)
F2
183
is the period from conception to birth, and the influences of nature refer to genetic factors in this development
Prenatal development
184
the law which states that two members of single gene pair separate from each o t h e r during gamete formation
Law of SEGREGATION
185
Na + -K+ pump
ACTIVE TRANSPORT
186
move large molecules and food particles across the plasma membrane with the expenditure of ATP; in other words, they utilize active transport.
Exocytosis and endocytosis
187
fusion of vesicles and molecules with the plasma membrane; secretes materials to the outside of the cell.
Exocytosis
188
the cell takes in the molecules via vesicles that fuse with the plasma membrane
Endocytosis
189
uptake of liquids
Pinocytosis
189
uptake of solids
Phagocytosis
190
Molecules or ions move down their concentration gradient from an area of high concentration to an area of low concentration, facilitated by various mechanisms such as simple diffusion, facilitated diffusion, and osmosis. This movement is driven by the random thermal motion of particles and does not require energy input.
Passive transport
191
Moves molecules or ions against their concentration gradient, from an area of low concentration to an area of high concentration, which requires the input of energy in the form of ATP. This energy allows transport proteins (such as pumps or transporters) to move molecules or ions against their concentration gradient, which is energetically unfavorable
Active transport
192
Cells acquire energy to build, store, break down, and rid themselves of substances
METABOLISM
193
large molecules are assembled and energy is stored
Biosynthetic pathway
194
large molecules are broken down into simple ones and energy is released
Degradative pathway
195
Metabolic Pathways
1. Energy-Acquiring 2. Energy-Releasing
196
Energy Acquiring: Anaerobic catabolism of glucose (6C) to pyruvic acid (3C x 2) which occurs in cytoplasm
Glycolysis
197
usually the longest stage. Cell splits and grows.
G1
198
energy used for replicating DNA
S
199
cell prepares to divide
G2
200
Meiosis or Mitosis
M
201
separation of the cellular cytoplasm due to constriction of microfilaments about the center of the cell
Cytokinesis
202
the law which states that genes on different chromosomes independently behave in the production of gametes. o Therefore, leading to the randomization of the genotypes/ phenotypes of the offspring
Law of INDEPENDENT ASSORTMENT
203
the trait that is usually manifested and is able to mask the effects of the recessive trait o Example: A girl has heterozygous straight hair (Cc). The big letter C refers to the dominant trait (straight) while, the small letter (curly) refer sto the recessive trait.
Dominant trait
204
the trait that is masked by the dominant trait
Recessive trait
205
refers to a trait that is pure-bred or has the same type of trait which could be both dominant or both recessive o Example: C-straight, c- curly. CC- homozygous straight, cc- homozygous curly
Homozygous
206
refers to a combination of a dominant and a recessive trait. o Example: C- straight, c-curly. Cc- heterozygous straight (via complete dominance)
Heterozygous
207
o Dominance is complete o Trait is governed by a single allele only o Genes are found on different chromosomes that is why their behavior is independent of each other o Genes are autosomal this, every parent has the same number of alleles No interaction between various genes o Trait has no selective value thus, every phenotype has equal chance of survival o Genetic material found in the chromosome
Assumptions of Mendelian Law
208
o A type of inheritance that neither traits from the parents is dominant to the other o Traits are 'blended' o Example: Crossing a red flower with a white flower yielding pink flowers as offspring is a manifestation of incomplete dominance
Incomplete dominance
209
o A type of inheritance that both traits from the parents are manifested. o Example: ABO blood typing system specifically bloodtype AB
Codominance
210
o A type of inheritance where-in multiple alleles affect a certain trait o Example: ABO blood typing systemis also inherited via multiple alleles. Various combinationsof blood allele A , B and O gives rise to different blood types
Multiple Alleles
211
o multiple numbers of genes affect a certain trait o height, skin color, eye color and intelligence
Polygenes
212
o this is a type of inheritance where-in genes responsible for the phenotypeof the organism is located in the 22 pairs of non-sex determining chromosomes. o There are two types of autosomal inheritance (1) autosomal dominant and (2) autosomal recessive
Autosomal Inheritance
213
o Dominant conditions are expressed in organisms with just one copy of the mutant allele o Affected males and females have equal probabilities of transmitting the trait to their offspring o Affected individual has only one copy of the normal gene and one copy of the faulty gene thus, offspring of each affected individual has 50% chance of getting the mutant allele o Huntington's disease, Achondroplasia and Polycystic Kidney Disease
Autosomal dominant
214
are not manifested when there is a normal copy of the gene recessive traits are manifested in males for having only one copy of the Xchromosome because there is no extra xchromosome to compensate for the mutant gene
X-linked recessive inheritance
215
o the mutant Manifested with only one copy of allele No father to son transmission o There is father to daughter transmission o All daughters of an affected father will have the disease because the father has only one X chromosome to transmit o woman affected has 50% chance having a child that is affected by the disease o Retinitis pigmentosa, Chondrodysplasia punctata, hypophosphatemic rickets
X-linked dominant inheritance
216
is a type of inheritance pattern that involves genes located on the sex chromosomes, which are the X and Y chromosomes. In humans, females have two X chromosomes, while males have one X and one Y chromosome. Since males only have one copy of the X chromosome, they are more likely to be affected by X-linked disorders than females.
Sex-linked inheritance
217
An X-linked disorder, which means it is carried on the X chromosome. Females have two X chromosomes, so they can be either carriers or affected by
Hemophilia
218
It is characterized by the presence of an extra copy of chromosome 21, which causes developmental and intellectual delays. In most cases, trisomy 21 occurs due to a random error during the formation of the egg or sperm, but it can also be inherited.
Trisomy 21 or Down Syndrome
219
are the leading cause of death worldwide. These include conditions such as coronary artery disease, heart failure, and stroke. Risk factors for these diseases include high blood pressure, high cholesterol, smoking, diabetes, obesity, and a sedentary lifestyle
Cardiovascular diseases
220
affect the lungs and breathing passages. Common examples include asthma, chronic obstructive pulmonary disease (COPD), and pneumonia. Environmental factors such as air pollution, second-hand smoke, and allergens can trigger or worsen these diseases
Respiratory diseases
221
o 3 FA’s and 1 glycerol o Transport, storage and insulation o 2 forms of Phospholipids in an aqueous environment: Micelle and Phospholipid bilayer
lipids
222
o Watson-Crick Model: Nucleotides (monomer) are connected to each other by phosphodiester bonds o Nucleotide is made up of three components: nitrogenous base, sugar (ribose, deoxyribose) and phosphate group o The nitrogenous bases are adenine, guanine, cytosine, thymine, uracil. o Base Pairs are connected by Hydrogen Bonds
Nucleic Acids
223
when fatty acid molecules are broken down in mitochondria to generate actyl-coA.
Beta-oxidation
224
chemical reaction between two molecules (amino acid containing amine (NH2) and a keto acid (=O). Amino acid becomes keto acid and keto acid becomes amino acid.
Transamination
225
process that generates NADPH and pentoses. This is an alternative to glycolysis. Primary role is anabolic and takes place in cytosol or in plastids of plants
Pentose phosphate pathway
226
biological response of a system to changes in predetermined set points of the body functions in maintaining homeostasis
Feedback mechanisms
227
most common mechanism; the output reduces the effect of the original stimulus; i.e. thermoregulation
Negative feedback
228
the output enhances the effect of the original stimulus; i.e. oxytocin production during labor
Positive feedback
229
collection of structures, organs, and glands that work in concert to ingest food, break it into molecules that can be absorbed by the circulatory system, and eliminate solid waste from the body.
DIGESTIVE SYSTEM
230
only carbohydrates are broken down
Oral Cavity
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secretes salivary amylase which breaks down starch; chewing or mechanical digestion is also carried out; a bolus or ball of food is formed
Mouth
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back of the throat; it has a structure called the epiglottis that blocks food from going down the windpipe or trachea.
Pharynx
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food tube that transports bolus down to the stomach via a smooth muscle contraction called peristalsis
Esophagus
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only protein is broken down
Stomach
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a digestive fluid with pH of about 2 that aids digestion
Gastric Juice
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a protease called pepsinogen until food is present in the stomach
Pepsin
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food and gastric juice that is processed in the stomach
Acid Chyme
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all 3 macromolecules (carbohydrates, lipids, and proteins) are broken down: i. Organ that digests most food and absorbs it into the blood.
Small Intestine
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first part of the small intestine where digestion takes place.
Duodenum
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main purpose is to reabsorb water; also creates feces and eliminates them through the rectum or end of the large intestine
Large Intestine or Colon (no digestion)
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The Effects of Irregular Eating Habits on the Stomach
Ulcer One of the main consequences of irregular eating habits is the formation of ulcers. Without food to buffer the effect of these acidic juices, they can start to digest the stomach lining, leading to the formation of ulcers.
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are specialized cells found in the heart that are responsible for pumping blood throughout the body. These cells are interconnected by regions of intercalated discs that allow them to function as a synchronized unit
Cardiac muscle cells
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are specialized structures that connect adjacent cardiac muscle cells. o They contain two main structures: desmosomes and gap junctions.
Intercalated discs
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are protein complexes that help to anchor adjacent cells together. o They are important for maintaining the structural integrity of the heart and for transmitting the force of contraction from one cell to the next.
Desmosomes
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are channels that allow ions and small molecules to flow between cells. o They are important for synchronizing the electrical activity of the cells and ensuring that they contract in a coordinated manner
Gap junctions
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initiate the electrical activity in the heart, these cells are transmitted through the intercalated discs to the cardiac muscle cells, resulting in coordinated contraction of the heart.
pacemaker cells
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are essential for the proper function of cardiac muscle cells and the efficient pumping of blood throughout the body.
Intercalated discs
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is the process by which muscles generate tension and produce force. It involves the activation of muscle fibers, which are composed of myofibrils. Each myofibril contains sarcomeres, the basic unit of muscle contraction
Muscle contraction
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The energy required for muscle contraction comes from the hydrolysis of? ________
hydrolysis of ATP
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blood mixes with internal organs directly. Insects, arthropods, and mollusks have an open circulatory system.
Open Circulatory System
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blood is contained within blood vessels that lead to the organs. Earthworms, octopi, and vertebrates have a closed circulatory system
Closed Circulatory System
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one ventricle, one atrium with gill capillaries allowing for gas exchange
Fish
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one ventricle and two atrium; have lung and skin capillaries for gas exchange. Have double circulation or oxygen-rich blood going to the organs and oxygen deficient blood returning to the right atrium.
Amphibian
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two ventricles and two atrium, with lung capillaries for gas exchange. Also makes use of double circulation
Mammal
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Pumps blood
Heart
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Carry blood away from heart under pressure (DEOXYGENATED)
Arteries
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Carry blood toward heart (OXYGENATED); contains valves that prevent blood from flowing backward; contraction of skeletal muscles provide force
Veins
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carries blood with highest concentration of oxygen
Pulmonary Vein
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veins that drain the kidney. Connect the kidney to the inferior vena cava
Renal Vein
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carries deoxygenated blood from heart to lungs
Pulmonary artery
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blood vessel that conducts blood from gastrointestinal tract and spleen to the liver
Hepatic portal vein
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Exchange substance with nearby tissues, generally by diffusion
Capillaries
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Carry O2
Red blood cells
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Protect against infections
White blood cells
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Clots blood
Platelets
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Carries nutrients, wastes, antibodies, and hormones; regulates osmotic pressure
Plasma
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Carry lymph from tissues to heart; transport digested fat to cardiovascular system
Lymph Vessels
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Lymph Nodes —Filter lymph to remove microorganisms and debris
Lymph Nodes
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Lost fluid and protein is returned to the cardiovascular system
Lymph
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consists of the lungs and related structures; it delivers oxygen to, and removes carbon dioxide from, the circulatory system in humans via the functional units known as the alveoli.
Respiratory system
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defined as the uptake of oxygen (O2 ) and loss of carbon dioxide (CO2 )
Gas exchange
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specialized for gas exchange of terrestrial organisms. For an insect such as a grasshopper, the tracheae opens to the outside
Tracheal system and lungs
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Amphibians (frogs) are the only vertebrates that use skin along with lungs to promote gas exchange.
Lungs
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Control of Breathing: the lower part of the brainstem, maintains homeostasis by monitoring CO2 levels. ii. When CO2 levels are high, the CO2 reacts with water in the blood, dropping the pH of the blood it senses a pH drop and excess CO2 is exchanged for O2 .
Medulla oblongata
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Iron—containing protein of mammalian red blood cells
Hemoglobin
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maintains water, salt, and pH balance, and removes nitrogenous wastes (urea in humans) from the body by filtering the circulating blood
EXCRETORY SYSTEM
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carries unfiltered blood from the circulatory system to the kidneys for filtration
Renal Artery
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carries filtered blood from the kidneys back to circulatory system.
Renal Vein
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remove urea and toxins from the blood; produce urine; maintain salt, pH, and water balance of blood.
Kidneys (contain nephrons)
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synthesizes urea from ammonia; detoxifies other wastes.
Liver (role in excretion)
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carry urine from kidneys to bladder
Ureters
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stores and eliminates urine from the body
Bladder
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carries urine from the bladder to exterior of the body
Urethra
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in the kidneys filter blood, removing wastes and returning vital substances to the circulatory system. This is an example of coordinated cooperation
Nephrons
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receives input from internal and external sensors and relays that information to the brain, where integration occurs; the brain sends out nervous signals to different parts of the body that carry out actions in response
NERVOUS SYSTEM
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large portion of neuron that contains the nucleus and organelles
Cell body
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communicate the nervous signals from tips of neuron to the cell body
Dendrites
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transmit action potentials down their lengths
Axon
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insulate axons for faster action potential in the central nervous system.
Myelin Sheath
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insulate axons for faster action potential in the peripheral nervous system.
Schwann Cells
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gaps between the Schwann cells that allow for faster action potentials, hence faster communication.
Nodes of Ranvier
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the space between the end of the axon and the target; examples of targets include muscles or other neurons
Synapse
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convert action potential into chemical signal when an action potential triggers the release of its vesicles filled with neurotransmitters into the synaptic cleft
Axon terminals
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Provides location for transmission of nerve signal between two neurons
Synaptic Cleft
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consists of the brain and spinal cord.
Central nervous system
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consists of all the neurons outside the brain and spinal cord
Peripheral nervous system
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brings information from sense to organs to the central nervous system via afferent (incoming) neurons
Sensory division
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brings information from the brain to the body by efferent (outgoing) neurons, and is divided into voluntary and involuntary systems
Motor division
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hormone and neurotransmitter that functions to regulate heart rate, breathing, and fight or flight response of sympathetic nervous system
Adrenaline/Epinephrine
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water soluble essential nutrient
Choline
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neurotransmitter released from the sympathetic neurons to affect the heart
Noradrenaline/Norepinephrine
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Neurotransmitter in autonomic nervous system that acts on peripheral nervous system and central nervous system. Only neurotransmitter used in the motor
Acetylcholine
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detect stimuli and turn it into action potentials that travel to the proper region of the brain where the received sensation is processed to produce a perception
sensory receptors
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specific and nonspecific defenses used by the body to fight pathogens
IMMUNE SYSTEM
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organisms that cause infectious disease, including viruses, bacteria, protists, fungi, and small vertebrates
Pathogens
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those targeting specific pathogens by recognizing a specific foreign substance by its antigens and then marshaling the humoral and/or cell-mediated defenses
Specific defenses
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involves B cells, whic attack pathogens with antibodies
Humoral immune response
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involves T cells, which attack pathogens, cells infected with pathogens, and cancer cells by lysing them
Cell-mediated response
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is any substance that can provoke an immune response in the body. * This immune response can involve the activation of specialized white blood cells called B cells, which can produce specific proteins called antibodies.
Antigen
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can neutralize antigens in a number of ways, including blocking their ability to bind to other cells, marking them for destruction by other immune cells, or directly attacking and destroying them.
Antibodies
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is primarily transmitted through specific bodily fluids that contain the virus. Here are the common modes of transmission
Human Immunodeficiency Virus (HIV)
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the stage of development that occurs after the embryonic stage, during which the organs and tissues that were formed during the embryonic stage continue to mature and develop
Fetal stage
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the stage of development during which the neural tube, which gives rise to the brain and spinal cord, is formed
Neurulation stage
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the stage of development during which the embryo undergoes a series of complex morphogenetic movements that result in the formation of distinct germ layers, which give rise to specific tissues and organs
Gastrulation stage
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ithe stage immediately following fertilization, during which the developing embryo is composed of totipotent cells that have the ability to give rise to all cell types in the body. During the gastrulation stage, the removal of individual cells can cause significant developmental abnormalities and damage to the embryo, as the cells have already started to differentiate into specific germ layers that give rise to specific tissues and organs
Pre-gastrulation stage
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is a type of B vitamin that is essential for the proper growth and development of the fetus during pregnancy
Folic acid
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The study of the interactions among living things and their surroundings
ECOLOGIC RELATIONSHIP
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Capture energy from sunlight, CO2 and H2O – Most producers are photosynthetic
Photosynthetic organisms
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Capture energy from chemical compounds in the surroundings
Chemosynthetic organisms
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Eat only plants and fungi
Herbivores
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Eat both plants/fungi and animals
Omnivores
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Eat only animals
Carnivores
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Eat dead organic matter
Detrivores
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Break down organic matter into simpler compounds
Decomposers
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Manner in which energy moves through an ecosystem – Each ecosystem has its own unique trophic structure
Trophic Structures
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Autotrophs (Photosynthesizers, Chemosynthetic organisms)
Producers
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Herbivores and omnivores that eat producers
Primary consumers
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Carnivores and omnivores that eat herbivores
Secondary consumers
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Carnivore eats another carnivore
Tertiary consumers
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Consume decaying producers and consumers
Decomposers and Detrivores
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-Energy is lost in each step up a food chain -Only 10 percent of the energy from one level on the food chain is available to the next level
Food Chain
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-Many consumers and decomposers have more than one food source -Movement of energy occurs in complex webs rather than in simple chains
Food Webs
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are organisms that can produce their own food through the process of photosynthesis, using energy from sunlight to convert carbon dioxide and water into organic compounds. They are the foundation of the food chain and provide the energy and nutrients needed for all other organisms in the ecosystem. Examples of producers include plants, algae, and some types of bacteria
Producers
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are organisms that break down dead organic matter, such as dead plants and animals, and recycle the nutrients back into the ecosystem. They play an important role in the nutrient cycle and help to maintain the balance of the ecosystem. Examples of decomposers include bacteria, fungi, and some types of insects
Decomposers
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are organisms that consume producers, feeding on plants or algae. They are also known as herbivores. Examples of primary consumers include rabbits, deer, cows, and some types of insects
Primary consumers
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are organisms that feed on primary consumers, also known as carnivores. They obtain their energy and nutrients by consuming herbivores or other carnivores. Examples of secondary consumers include foxes, wolves, hawks, and some types of fish.
Secondary consumers