biology Flashcards

1
Q

What are the two Cell Cycles

A

Binary fission and mitosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Mitosis phases

A

Interphase
Prophase
Metaphase
Anaphase
Telophase
Cytokinesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happens during prophase

A

Chromosomes (DNA) replicates, chromatin condenses around histones into distinct chromosomes, at the same time thew centriole migrates the the end of the cell and spindle fibres form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What happens during metaphase

A

Spindle fibres attach to the centromere of each chromosome, causing them to align at centre of cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What happens during anaphase

A

Mitotic spindle pulls sister chromatids to opposite poles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What happens during telophase

A

Mitotic spindle disappears, nuclear envelope begins to reform, cell division begins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What happens during cytokenis

A

Cell divides, two daughter cells form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

G1 phase

A

Ensures cell has grown to correct size and has synthesised enough protein for DNA replication. Checks if DNA has been damaged and if there is enough nutrients and oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Synthesis

A

The cell copies its chromosome (DNA) into 2 sister chromatids
DNA REPLICATION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

G2 phase

A

The G2 checkpoint ensures that DNA has replicated properly in the S phase, and that the cell has enough resources for mitosis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Interphase consists of…

A

G1
Synthesis
G2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What happens during Interphase

A

the cell synthesises the necessary DNA, proteins, and organelles required for growth and replication (Figure 2). At this time, DNA in the nucleus exists as long chromatin threads instead of discrete chromosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is a prokaryotic cells method of reproduction?

A

Binary fission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is a eukaryotic cells method or reproduction

A

Mitosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cytokinesis in plant cells

A

because they have a cell wall, a cell plate first forms at the equator before separating into two cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Cytokinesis in animal cells

A

this occurs when a cleavage furrow develops and pinches the plasma membrane into two cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Stem cells

A

A stem cell is a cell which is unspecialised and capable of self renewal, All cells begin as stem cells and through the process of differentiate they develop into specialised cells with a particular function

18
Q

Different types of potency (The Prime Ministers Open Umbrella)

A

Totipotent
Pluripotent
Multipotent
Ogliopotent
Unipotent

19
Q

Describe and list an example for a totipotent cell

A

Stem cells that can differentiate into any cell type

A zyogte cell, any embryonic cell, placenta or umbilical

20
Q

Describe and list an example for a pluripotent cell

A

Stem cells that can differentiate into multiple cell types, anything in embryo except umbilical cord and placenta.

Embryonic stem cells, which are found in the early stages of a developing embryo (skin, hair, nerve)

21
Q

Describe and list an example for a multipotent cell

A

stem cells that can differentiate into a limited number of specialised cell types belonging to a specific tissue or organ. (specialises into 3 germ cells)

Ectoderm (skin, nervous system)
Mesoderm (muscle, bone, blood)
Endoderm (genitals, lungs, gastrointestinal)

22
Q

Describe and list an example for a oligopotent cell

A

Can change into a small number of specialised cells

Lymphoid cell and myeloid cell (red and white blood cells)

23
Q

Describe and list an example for a unipotent cell

A

Now specialised to complete 1 role

Killer T cells (remove virus and bacteria from body)

24
Q

DNA structure

A

4 bases always pair with the same base (a-t, t-a, c-g, g-c)
Adenine - Thymine
Cytosine - Guanine

25
Apoptosis
Is the natural and controlled death of cells within our body which plays an important role in our development and day to day lives
26
4 stages of apoptosis
1) Caspases are activated in the cell 2) Digestion of cell contents 3) Cell shrinks 4) Membrane bulging and breakage
27
What happens during the 1st stage of apoptosis
The mitochondria detect internal DNA damage, and release cytochrome C
28
What happens during the 2nd stage of apoptosis
Caspases cleave and intracellular proteins, which leads to the breakdown of organelles
29
What happens during the 3rd stage of apoptosis
The cell and nucleus shrink as intracellular material is broken
30
What happens during the 4th stage of apoptosis
as the cytoskeleton is digested, the structural integrity of the cell is weakened. The membrane warps and detaches from the cell in membrane-enclosed vesicles known as apoptotic bodies which contain the broken down intracellular material.
31
Errors of apoptosis
When the rate of apoptosis is decreased, cell growth increases resulting in tumours. When the rate of apoptosis increases neurological disorders can from.
32
Necrosis
Necrosis is the unregulated death of cells initiated by significant damage which causes the cell to swell, burst, and release cell contents into the surrounding environment. This may lead to inflammation and damage in nearby cells and tissues.
33
4 main sources of stem cells
embryonic tissues, fetal tissues, adult tissues and differentiated somatic cells
34
Integrity
the commitment to searching for knowledge and understanding and the honest reporting of all sources of information and communication of results, whether favourable or unfavourable, in ways that permit scrutiny and contribute to public knowledge and understanding.
35
Justice
the moral obligation to ensure that there is fair consideration of competing claims; that there is no unfair burden on a particular group from an action; and that there is fair distribution and access to the benefits of an action.
36
Beneficence
the commitment to maximising benefits and minimising the risks and harms involved in taking a particular position or course of action.
37
Non-maleficence
involves avoiding the causations of harm. However, as positions or courses of actions in scientific research may involve some degree of harm, the concept of non-maleficence implies that the harm resulting from any position or course of action should not be disproportionate to the benefits from any position or course of action.
38
Respect
involves consideration of the extent to which living things have an intrinsic value and/or instrumental value; giving due regard to the welfare, liberty and autonomy, beliefs, perceptions, customs and cultural heritage of both the individual and the collective; consideration of the capacity of living things to make their own decisions; and when living things have diminished capacity to make their own decisions ensuring that they are empowered where possible and protected as necessary.
39
5 Ethical principles
Integrity Justice Beneficence Non-maleficence Respect
40
Stakeholders
anyone who is invested in the process, or affected by it e.g the scientists working on the treatment, politicians who might create ‘rules’ or guidelines around its use, the Catholic church who might disagree with the creation of stem cells.
41
DNA replication
Helicase ‘unzips’ the DNA strand, DNA polymerase assemble or ‘rebuild’ the DNA strands, ligase ‘glues’ them together.
42
Concerns in society
Society will have concerns about a range of things, think of how controversial things like COVID vaccinations and lockdowns were. They were designed to protect people with the best intentions in mind, but it wasn’t necessarily supported. Stem cell usage will possibly be the same where people will be happy for the treatment which may help people, but worried about what could also happen if people are able to create stem cells which can turn into anything, but they are not regulated.