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Biologiska Läkemedel Psoriasis > Biologiska Läkemedel Psoriasis > Flashcards

Biologiska Läkemedel Psoriasis Flashcards

1
Q

ixekizumabs/Taltz verkningsmekanism

A

Humaniserad monoklonal antikropp som binder cytokinerna IL-17A & IL17-AF

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2
Q

ixekizumabs försäljningsnamn

A

Taltz (producent Lilly)

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3
Q

ixekizumab/Taltz indikation

A

Plackpsoriasis
Psoriasisartrit

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4
Q

ixekizumab/Taltz kontraindikationer

A

Infektion ink obehandlad latent tuberkulos
Graviditet
Amning

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5
Q

ixekizumab/Taltz relativa kontraindikationer

A

IBD
malignitet

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6
Q

ixekizumab/Taltz biverkningar

A

Vanliga: reaktion vid injektionsstället, luftvägsinfektion, tinea, orofaryngeal smärta, illamående, oral herpes
Mindre vanliga: oral candidos, neutropeni, trombocytopeni, urtikaria, cellulit

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7
Q

brodalumab försäljningsnamn

A

Kyntheum (LEO Pharma)

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8
Q

brodalumab försäljningsnamn

A

Kyntheum (LEO Pharma)

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9
Q

brodalumab/Kyntheum verkningsmekanism

A

Monoklonal antikropp som binder till IL-17RA, blockerar IL-17A, IL17F, IL-17AF heterodimer och IL-25.

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10
Q

brodalumab/Kyntheum indikation

A

Plackpsoriasis

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11
Q

brodalumab/Kyntheum absoluta kontraindikationer

A

infektion ink obehandlad latent tuberkulos
Aktiv Crohns sjukdom
Graviditet
Amning

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12
Q

brodalumab/Kyntheum relativa kontraindikationer

A

Malignitet
Depression ink självmordstankar och -beteende
Tidigare IBD

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13
Q

brodalumab/Kyntheum biverkningar

A

Vanliga: Luftvägsinfektion, influensa, reaktion vid injektionsstället, tinea, orofaryngeal smärta, illamående, diarré, oral herpes, neutropeni, trötthet
Mindre vanliga: Candidainfektioner, konjunktivit

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14
Q

guselkumab/Tremfya verkningsmekanism

A

Monoklonal antikropp som binder selektivt till IL-23 och inhiberar Th17-medierad inflammation

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15
Q

guselkumab försäljningsnamn

A

Tremfya (Janssen)

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Biologiska Läkemedel Psoriasis (1 decks)

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