biological therapy for schizophrenia Flashcards

1
Q

what can the drugs be divided into

A
  • typical antipsychotics
  • atypical antipsychotics
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2
Q

what are typical antipsychotics

A
  • the first generation of drugs for schizophrenia.
  • been used since 1950’s.
  • work as dopamine antagonists
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3
Q

give examples of typical antipsychotics

A
  • chlorpromazine
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4
Q

how can typical antipsychotics be taken

A
  • tablets
  • syrups
  • injections
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5
Q

if taken orally what is the maximum mg that can be taken for typical antipsychotics

A

1000

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6
Q

what is the average amount people take for typical antipsychotics

A

400-800mg

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7
Q

what are atypical antpsychotics

A

developed in the 1960’s and trialled in early 70’s.
- used when other treatments failed\

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8
Q

what are examples of atypical antipsychotics

A
  • Clozapine
  • resperidone
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9
Q

what did Marder and Meibach (1994) research

A
  • studied schizophrenic patients who took resperidone compared to haloperidol or a placebo
  • showed significant improvement in both positive and negative symptoms.
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10
Q

how do drugs link to issues and debates

A

is biologically reductionist as they reduce complex disorders os schizophrenia down to be treated to using tablets/syrups and injections.

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11
Q

what are the strengths to drug treatments

A
  • there is a body of compelling research evidence which suggests that antipsychotics are an affective treatment for scz
  • antipsychotics are most effective at treating patients with the most severe symptoms who may not be treatable using non-drug therapies (Furakawa et al. 2015)
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12
Q

what are limitations for drug therapies

A
  • patients with milder, less extreme forms of schizophrenia benefit less from taking antipsychotics and may additionally experience adverse side effects.
  • it is not clear as to how effective antipsychotics are in preventing relapses in patients who are in remission.
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