biological explanations of schizophrenia Flashcards
genetic basis of schizophrenia
family studies
candidate genes
mutation
role of dopamine
is involved in schizophrenia because it is featured in the functioning of brain systems related to the symptoms of schizophrenia.
family studies ( case study )
Gottesman large scale study someone with an aunt with schizophrenia has a 2% chance of developing it ,9% for sibling + 48% for identical twin.
original DA hypothesis ( hyperdopaminergia linked to sub cortex)
higher dopamine activity in subcortex ( central areas of the brain) associated with hallucinations + poverty of speech
updated version ( hypodopaminergia
linked to prefrontal cortex )
Updated hypothesis has added low levels of DA in the prefrontal cortex ( responsible for thinking) could explain negative symptoms
what are 2 strengths of biological explanation of schizophrenia?
- strength strong evidence base.
- is support for dopamine in the symptoms of schizophrenia.
what are 2 limitations of biological explanations of schizophrenia?
- is evidence for environmental risk factors
- is evidence for a central role of glutamate