biological effects of ionising radiation Flashcards
what are the 2 forms of ionising radiation
by products of radioactive decay e.g gamma rays
artificially produced electromagnetic radiation e.g x rays
what is the difference between an atom and an ion
atom has equal numbers of protons and electrons
ion has an unequal number of protons and electrons giving it a positive or negative charge
what is an ion pair
newly formed ion and its displaced electron
what effect does ionising radiation have on atoms
turns atoms into ions by displacing electrons
what is the most significant effect in humans of ionising radiation and how does this cause an issue
DNA damage
Faulty repair of the damage leads to abnormal cell population development and possible cancer development
single strand break is an easy repair but double strand break repair is difficult and may lead to mutations
in what two ways can DNA be damaged due to ionising radiation
Direct - radiation interacts with atoms of a DNA molecule
Indirect - radiation interacts with water in a cell producing a free radical which can diffuse short distances and cause DNA damage
what 2 things is tissue radiosensitivity dependent on
function of cells that make up tissue
are the cells actively dividing
more dividing = more radiosensitive e.g stem cells are very radiosensitive
absorbed dose (Gy)
measures energy deposited by radiation
Equivalent dose (Sv)
absorbed dose multiplied by radiation weighting factor
Weighting factor dependent on type of radiation - x ray WF = 1, gamma ray WF = 20
Effective dose (Sv)
equivalent dose multiplied by tissue weighting factor
linear no threshold model
estimates the long term biological effects of radiation
assumes radiation is always harmful with no safety threshold, several small doses is equal to one large dose
deterministic effects of radiation
concerns tissue reactions that only occur above a certain threshold therefore effects are dependent on dose recieved
rare in radiology , effects take several days to appear
perhaps radiotherapy and hairloss
stochastic effects of radiation
uses LNT model
no known threshold i.e no dose below which no effects will occur
risks are always present no matter how low the dose
effects can develop years after exposure and there are 2 types
somatic - disease/disorder e.g cancer
genetic - abnormalities in descendants
Does pregnancy need to be taken into account when taking dental x rays
no as dose to foetus is so low - usually less than daily background radiation it would receive
beam is pointed no where near the abdomen
name 3 sources of background radiation
cosmic rays
radionucleotides from diet and air
gamma radiation from soil/rocks etc