Biological Behavior Flashcards
neuron
Unit of nervous system
Soma
Central cell body contains nucleus and is where most of biosynthetic activity of cell take place
Slender projections include
- 1 Long axon carry action potentials away the cell body
- Many dendrites receive signals
Bipolar
Neuron with one dendrite
Multipolar
Neuron with many dendrite
Synaptic knobs
Where axon branch and terminate to form connection with target cell
Synaptic cleft
A very small gap where chemical messengers are released and travel across to reach target cell, when action potentials travel down an axon and reach synaptic knob
Nerve
Large bundle of many different axons from different neurons
Resting membrane potential
Electric potential across plasma membrane of -70mV
2 Primary membrane proteins establish the resting membrane potential
- Na+/K+ ATPase
- K leak channels
How resting membrane potential work
- Na+/K+ ATPase pump 3 Na outgo the cell and 2 K into the cell with hydrolysis of 1 ATP -> High Na outside cell, high K inside cell
- Leak channels always open to allow K flow out the cell. Few Na leak channel still in the cell
- Result: Interior of cell more negative than exterior
Polarized
Negative inside, positive outside
How depolarization work?
- Voltage-gated Na channels open by depolarization from -70mV to -50mV threshold potential
- In threshold or higher, channel open fully. Below threshold (ex -60mV), channel close.
- Channel open to let Na flow into cell and depolarize this membrane to +35mV before inactivating
How repolarization work?
- Voltage-gated K channel slowly open than voltage-gated Na channels and stay longer
- Close at -90mV by repolarization
myelin
Insulating sheath wrap axons of many neurons
Schwann cells
A glial cell in conjunction with neuron (PNS) makes myelin and speed up conduction of action potentials along axon
What happen to axonal plasma membrane in myelin?
- No membrane depolarization
- No voltage-gated Na and K channel
nodes of Ranvier
Periodic gaps in myelin where voltage-gated Na and K channels are concentrated
What myelin do?
Speed the movement of action potentials by forcing them to jump from node to node
saltatory conduction
rapid jumping conduction in myelinated axons
Glial cell
Non-neuronal cell support structurally and metabolically to neuron
Oligodendrocytes
Glial cell in CNS has same function to Schwann cell
Astrocytes
Glial cell in CNS guide neuronal development and regulate synaptic communication by regulation of neurotransmitter levels
Microglia
Glial cell in CNS remove dead cells and debris