Biological basis of behavior and addiction Flashcards

1
Q

physiologic responses that occur more or less unconsciously when the brain detects situations

A

emotion

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2
Q

the conscious experience resulting from these emotions

A

feeling

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3
Q

some stimuli evoke emotions automatically

A

emotional competence

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4
Q

What are roles of the limbic system?

A

emotional behavior

memory

integration of homeostatic responses

sex

motivation

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5
Q

important in feelings of pleasure and may be critically important in addiction

A

nucleus acuumbens

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6
Q

learn to associate predictive stimuli with danger, harm, or pain

A

conditioned fear

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7
Q

what is required for fear conditioning?

A

amygdala

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8
Q

response of fear is the HT releasing CRF to release cortisol from adrenals in order to

A

suppress inflammation

catabolic state

heighten arousal

survival response

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9
Q

anxiety is …

A

triggered in the absence of threatening stimulus

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10
Q

Who might have an enlarged amygdala?

A

PTSD pts

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11
Q

What two spots are able to generate new neurons later in life?

A

hippocampus and olfactory bulb

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12
Q

implicit memory includes

A

unconscious, perception and recall

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13
Q

Things learned in a happy state are better recalled in..

A

a happy state

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14
Q

pts with hippocampus damage will retain..

while lacking…

A

conditioned response to fearful stimuli

declarative memory of stimuli (lack conscious recall)

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15
Q

a brief high frequency train of stimuli (tetanus) increases the slope of the EPSPs in the target hippocampal neurons

A

LTP - long term potentiation

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16
Q

NMDA antagonists disrupt some aspects of…

A

spatial memory

17
Q

amphetamine and cocaine increase…

A

dopaminergic neurotransmission

18
Q

What may be the earliest clinical sign of subfrontal meningioma?

A

anosmia

19
Q

inappropriate use of a drug for a non medical purpose

A

drug abuse

20
Q

uncontrolled and compulsive use of a drug

A

addiction

21
Q

increased dose required for the same effect

A

tolerance

22
Q

What group of drugs have the highest abuse potential?

A

schedule 1

23
Q

no accepted medical use and high potential for abuse

A

schedule I

24
Q

cocaine, methamphetamine, methadone, oxycodone, methylphenidate are all

A

schedule II

25
Q

federarl supported tx for opiate addiction is through what with what rx?

A

CSAT - center for substance abuse treatment

methadone or buprenorphine

26
Q

The Ventral tegmental area projects to the … releasing …

A

nucleus accumbens

dopamine

27
Q

What drug is used to eliminate nausea, vomiting, sweating, tachycardia, and hypertension of withdrawal?

A

clonidine

28
Q

Local anesthetics for dental work should be used… epi if the pt has used meth in the previous 24 hours

A

without epi

29
Q

alveolar damge and hemorrhagic alveolitis that occurs within 2 days after smoking crack cocaine

A

crack lung