biological approach to explaining OCD Flashcards

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1
Q

what are the 2 explanations?

A
  1. genetic explanation
  2. neural explanation
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2
Q

what are the key details of the genetic explanation?

A
  • inherit genetic vunerability
  • candidate genes
  • ocd is polygenic
  • aetiologically heterogenous
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3
Q

explain genetic vulernability in relation to OCD

A

individuals have greater vunerability to first degree relatives who have OCD

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4
Q

what is Lewis’ research?

A

37% OCD patients had parents with OCD. 21% had siblings with OCD

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5
Q

explain candidate genes in relation to OCD

A

specific genes that could be responsible for OCD. genes are involved with regulating development of serotonin system

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6
Q

how is OCD polygenic ?

A

its caused by combination of genetic variations to increase vunerability

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7
Q

what is Taylor’s research?

A

found theres upto 230 different genes that may be involved with OCD

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8
Q

what does the stress- diathesis model suggest?

A

certain genes leave people more LIKELY to develop mental disorder but not certain. environmental stress triggers condition

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9
Q

explain aetiologically heterogenous in relation to OCD

A

there are different complex forms of OCD so different genes involved in cause of each type. the origins of OCD vary from one person to another

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10
Q

evaluation of genetic explainations

A

S: good supporting evidence- Nestadt twin studies
S: evidence from animal studies- mice
L: could be environmental risk factors- cam trigger/ increase risk of developing OCD

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11
Q

what are the key details of the neural explanation?

A
  • role of neurotransmitters: serotonin
  • brain structures
  • the worry circuit
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12
Q

explain the role of neurotransmitters

A
  • low levels of serotonin means normal transmission of mood relevant info doesnt take place so mood/mental processes are affected.
  • some OCD assicoated with reduced levels of serotonin caused by SERT gene (causes low level of serotonin)
  • some OCD explained by reduction in functioning of serotonin system in brain
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13
Q

explain brain structures

A

some OCD associated with impaired decision making bc of brain structures:
- lateral frontal lobe: responsible for logical thinking + decision making= explains obsessive thoughts/complusions
- left parahippocampal gyrus: processes unpleasant emotions= explains disgust/anxiety/guilt

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14
Q

explain the worry circuit

A

two brain areas associated with OCD:
1- orbit frontal cortex: sends worry signals that are picked up by thalamus + directed around body
2- caudate nucleus: suppresses some of worry signals

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15
Q

what happens if the caudate nucleus is not working properly?

A

the worry signals do not get suppressed and a person worries too much which can cause OCD

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16
Q

what is the worry circuit supported by?

A

PET scans- shows heightened activity in OFC when holding a dirty cloth. PET scans= objective and scientific

17
Q

evaluation of neural explanations

A

S: some supporting evidence- antidepressants + parkinsons disease
L: cause and effect- result of OCD rather than cause- correlation
L: OCD link may be co-morbidity with depression