Biologic Flashcards
1
Q
What is post-translational modification and give examples
A
A covalent alteration of a peptide sequence that occurs after the peptide has been synthesized.
Examples: Glycosylation, Sulfation, Phosphorylation, Acetylation.
2
Q
What are good organisms/hosts for synthesizing biologics
A
Cannot be a prokaryote as they are not capable of PTM.
* Human kidney cells
* Chinese hamster cells
3
Q
A
