Biolingo- cell membrane and extracellular membrane Flashcards

1
Q

I am a nucleotide and I have ribose as a sugar. What am I?

A

RNA

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2
Q

What is the definition of Nucleoside?

A

A componant of a nucleotide that is composed of a sugar group (ribose or deoxyribose), and a nitrogenous base

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3
Q

True or False: A nucleoside is a nucleic acid monomer. It is composed of a sugar, a phosphate group and a nitrogenous base.

A

False. Nucleosides are composed of a sugar and a nitrogenous base but they do not have a phosphate group. In fact, nucleotides are the monomers of nucleic acid.

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4
Q

I am a protein that separates parental DNA strands during DNA replication. What am I?

A

Helicase

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5
Q

Which missense mutation in the active site of an enzyme is least likely to affect its enzymatic activity?

A

Valine, a nonpolar amino acid to Leucine, a nonpolar amino acid

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6
Q

Describe DNA.

A

A nucleotide polymer with a bidirectional structure carrying the genetic information of living organisms and some viruses.

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7
Q

I am a DNA fragment newly synthesized on the discontinuous strand. What am I?

A

Okazaki fragment

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8
Q

Complete the following sentence: Replication and transcription begin at specific sites on the chromosome. Replication starts at the ________ whereas transcription begins at the _________ after the promoter.

A

Origin ; Start site (TSS)

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9
Q

Which anticodons corresponds to the codon GUA?

A

CAU

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10
Q

Complete the following sentence: Often an _______ codes for a specific protein domain.

A

Exon

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11
Q

What am I? A type of mutation that can affect multiple genes.

A

Chromosomal rearrangement

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12
Q

What determines where transcription begins?

A

Promoter sequences on DNA

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13
Q

What am I? A protein that reduces the tension in the replication fork.

A

DNA gyrase

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14
Q

Which mechanisms regulate gene expression in eukaryotes?

A

Methylation of DNA; Activators and repressors that regulate the transcription of a gene; and Micro-RNAs that prevent the production of a particular protein

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15
Q

Example of a Watson-Crick base pair in DNA.

A

Adenine - Thymine; Guanine - Cytosine

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16
Q

Describes a genetic mutation.

A

Permanent modification to the genome of an organism

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17
Q

I am a protein that binds to a specific sequence of DNA in order to reduce the transcription of a specific gene. What am I?

A

Repressor

18
Q

What will be added to the 5’ end of a mature messenger RNA?

A

A Cap

19
Q

What am I? A point mutation that has no effect on the amino acid sequence of a protein.

A

Silent mutation

20
Q

Describe transfer RNA.

A

RNA that brings amino acids to ribosomes during protein synthesis.

21
Q

I am an enzyme that synthesizes ribosomal RNA.

A

RNA polymerase I

22
Q

I am a nucleotide and I have ribose as a sugar.

A

RNA

23
Q

True or False: Promoters are required for the initiation of transcription in eukaryotes and prokaryotes.

A

True, promoters are required in both domains. However their organization is very different between eukaryotes and prokaryotes.

24
Q

I am an enzyme that binds together Okazaki fragments.

A

DNA ligament

25
Q

How are metabolic pathways regulated in the long term?

A

By the expression of genes that code for the enzymes needed for this pathway.

26
Q

I am an enzyme that synthesizes messenger RNA.

A

RNA polymerase II

27
Q

I am a non-coding DNA sequence that protects DNA from shortening during replication/

A

Telomeres

28
Q

I am a protein that binds to a specific sequence of DNA in order to stimulate the transcription of a specific gene.

A

Activator

29
Q

Where are chaperone proteins mostly found?

A

Golgi apparatus and cytoplasm

30
Q

What is a replication model of DNA where parent strands each associate with a new complementary strand.

A

Semi-conservative model

31
Q

Glycosylation is a potential protein modification in eukaryotes.when does this modification take place?

A

Post-translation

32
Q

What is an aromatic compound that pairs with a purine to form the double alpha helix of DNA.

A

Pyrimidine

33
Q

What is composed of a modified guanine and a methyl group attached to the 5’ extremity of mRNAs?

A

5’ cap

34
Q

What is the step in the dogma of molecular biology in which mRNA is used as a matrix to synthesize proteins?

A

Translation

35
Q

DNA has a ____ structure that protects stabilizes it.

A

Helicoidal

36
Q

The central dogma involves _____.

A

replication, transcription, and translation

37
Q

In the _____ transport vesicles continuously leave the Golgi apparatus to guise with the plasma membrane.

A

Constitutive secretory pathway

38
Q

What is an epigenetic process resulting in the addition of a methyl group to a cytosine.

A

DNA methylation

39
Q

During translation, _____________ reads an mRNA molecule and assembles the polypeptides to form proteins according to the sequence read on the mRNA.

A

Ribosome

40
Q

Explain the difference between the synthesis of a leading strand and a lagging strand.

A

During synthesis, DNA polymerase can only add nucleotides at the 3’ end of the new strands.