biolab Flashcards

cholesterol

1
Q

where does cholesterol synthesis take place?

A

mainly in liver , and using simple molecules like acetate.
it also derived from dietary intake

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2
Q

what is cholesterol circulated with into circulation?

A

specific liboproteins

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3
Q

role of thyroid?

A

synthesis and degradation of cholesterol and triglycerides

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4
Q

what does bile acid do?

A

polar derivative of cholesterol that acts as detergents in the intestine, emulsifying dietary fats to make the more readily accessible to digestive lipases.

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5
Q

cholesterol uses-

A

important component of the cell membrane assisting in establishing proper membrane permeability and flexibility.

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6
Q

normal range of cholesterol in human-

A

150-250 mg/dl

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7
Q

primary factor for coronary heart disease-

A

cholesterol

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8
Q

elevated levels of serum cholesterol are associated with?

A

atherosclerosis, necrosis, diabetes mellitus.

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9
Q

low levels of cholesterol are associated with?

A

anaemia, hyperthyroidism, malabsorbtion

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10
Q

cholesterol esters + cholesterol esterase->

A

cholesterol + fatty acids

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11
Q

cholesterol + o2 + cholesterol oxidase ->

A

cholest-4-ene-3-one + h2o2

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12
Q

2h2o2 + phenol + 4-AAP + POD ->

A

quinononeimine dye(red) + h2o

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13
Q

what wavelength is absorbance of this quinoneimine dye measured at

A

505 (490-510) nm

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14
Q
A
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