Bioinorganic Flashcards
Explain the pH dependence of uncatalyzed + SOD catalysed disproportionation of superoxide in aq soln?
Give examples of proton coupled electron transfer (PCET) reaction
What is the function of Mn and Ca as M centres in PSII OEC?
Cl- is an anion and needed for binding to neutralise the charge
What is the role of tyr z residue in PSII?
What are 2 examples of Blue copper proteins and describe their structures + preference for donors?
- Azurin - e- transport enzyme in bacterial photosynthesis
Cu I - Plastocyanin
e- transport enzyme in photosystem II in plants + algae
What is the active site of Azurin and Plastocyanin?
Why is PCET essential in photosynthesis?
Where is Rubridoxin found, describe its active site and how the entatic effect
Rb is found anaerobic bacteria
Active site = Fe metal is coordinated by 4 S cys atoms
* Regular Td structure
* Fe centre is held at intermediate Fe-S bond lengths unsuitable for free FeII or FeIII complex in soln
* M distorted towards TS -> rapid cycling between OS
Cytochrome c oxidase
Why do fluoride ions inhibit plant growth?
High affinity for calcium replacing the essential
chloride ion at the active site – this fluoride complex is likely to be
highly stable and alter the pKa of the calcium bound water
Which mechanism does MnIIISOD go by?
It binds other anions which suggest inner sphere
Which mechanism does the oxidation of * FeIISOD go by?
Exclusively outer sphere
What reaction does human carbonic anhydrase catalyse and write down the equation?
The hydrogenation of CO2 and the dehydrogenation of carbonic acid
Draw the mechanism for HCA II
See notes
What metal is found in chloroplasts?
Manganese-oxo species
