Bioinformatics

Question 0

Definition of orthologs

Answer 0

Preform identical or very similar functions in different species/separated by even of speciation

Question 1

Conservative vs nonconservative vs invarient

Answer 1

Conservative- tolerant for change because of similarities (+)
Nonconservative - Hypervariable (-)
Invariant - mutations are intolerable and wont see a change. Has resistants to change despite evolution

Question 2

Define paralogs

Answer 2

Preform different functions with in on species. Separated by event of genetic duplication.

Question 3

Define Homologs

Answer 3

A gene related to a second by descent from common ancestor. Can be orthologs or paralogs

Question 4

What is shuffling?

Answer 4

assessing the significance of our sliding alignment by “shuffling,” or randomly rearranging, one of the sequences. If alignment score is greater than the shuffling it strongly suggests similarity