Biofilms Flashcards
Define Acquired Pellicle
A thin ACELLULAR film (about 1mcm) derived mainly from salivary glycoproteins, that forms over the surface of a cleansed tooth crown when it is exposed to the saliva
Define Biofilm
Complex, highly organized, 3D communal arrangement of multiple microorganism toes adhering to a surface where moisture & nutrients are available
Time it takes for acquired pellicle to form on the tooth
Quickly reforms within minutes
Primary colonizers
Supragingival
Non-pathogenic: streptococcus & Actinomyces
Adhere directly to pellicle
Within 2 days surface is colonize mainly by: gram+ bacteria, aerobic, cocci
Secondary colonizers
Rapid growth bacterial colonization
Production of extracellular slime layer
Slime layer helps anchor bacteria & protect it
Bacteria attached to tooth surface excrete a glue-like surface
Aerobic bacteria
Require____
Found_____
Oxygen
Supragingivally
Anaerobic bacteria
Require____
Found_____
NO oxygen
Subgingivally
Materia Alba
White, cheese like accumulation of:
Food debris
Microorganisms
Desquamated epithelial cells
Blood cells deposited around the teeth at the gum line
(Can be flushed off with forceful water spray)
(Role in formation of plaque)
Calculus
Abnormal concretion deposited on tooth surfaces composed of calcium phosphate and carbonate mineral salts in combination with organic matter
4 stages of biofilm development
1) attachment of bacteria to solid surface
2) initial colonization
3) secondary colonization
4) formation of mature subgingival biofilms
Importance of plaque removal
The longer the oral biofilm remains undisturbed, the greater its pathogenic potential for the host
Pathogenic oral biofilm causes disease. T/F?
True.
Calculus causes disease. T/F?
False.
Pathogenic oral biofilms do