Bioenergetics (CHPT 3) Flashcards
How is Acetyl-CoA formed?
- A two carbon molecule formed from pyruvate produced by glycolysis or from the oxidation of fatty acids or amino acids
Activation energy
- Energy required to initiate a chemical reaction
What is adenosine diphosphate (ADP)?
- A molecule that combines with inorganic phosphate to form ATP
What is Adenosine triphosphate (ATP)?
- The high energy phosphate compound synthesized and used by cells to release energy for cellular work
Aerobic
- in the presence of oxygen
Anaerobic
- without oxygen
ATPase
- enzyme capable of breaking down ATP to ADP + Pi + energy
ATP-PC System
- term used to describe the metabolic pathway involving muscle stores of ATP and the use of phosphocreatine to re-phosphorylate ADP.
- this path use use at the answer of exercise and during short term high intensity work
Beta oxidation
- breakdown of three fatty acids to form acetyl-CoA
Bioenergetics
- The chemical process involved with the production of cellular ATP
Cell membrane
- The lipid bilayer envelope that encloses cells
- sacrolemma in muscle cells
Chemiosmotic hypothesis
- The mechanism to explain the aerobic formation of ATP and mitochondria
Citric acid cycle/Krebs cycle
- A key metabolic pathway located in the mitochondria
- A series of chemical reactions used to harness useable energy through the oxidation of acetyl-CoA Derived from carbohydrates, fats, and proteins
Coupled reactions
- The linking of energy liberating chemical reactions to drive energy requiring reactions
Cytoplasm
- The contents of the cell surrounding the nucleus
- sacroplasm in muscle cells
Electron transport chain
- A series of cytochromes in the mitochondria that are responsible for oxidative phosphorylation
Endergonic reactions
- Energy requiring reactions
Enzymes
- proteins that lower the energy of activation and, therefore, catalyze chemical reactions
- Regulate the rate of most metabolic pathways
Exergonic reactions
- Chemical reactions that release energy
Flavin adenine dinucleotide (FAD)
- serves as an electron carrier in bioenergetics
Glucose
- A simple sugar that is transported via the blood and metabolized by tissues
Glycogen
- A glucose polymer synthesized in cells as a means of storing carbohydrate
Glycogenolysis
- The breakdown of glycogen into glucose
Glycolysis
- A metabolic pathway in the cytoplasm of the cell that results in the degradation of glucose into pyruvate or lactate
Inorganic
- substances that do not contain carbon
Inorganic phosphate (Pi)
- A stimulator of cellular metabolism
-  use with ADP to form ATP in the electron transport chain
Isocitrate degydrogenase
- rate limiting enzyme in the Krebs cycle that is inhibited by ATP and stimulated by ADP and Pi
Lactate
- A three carbon molecule that is a potential and product of glucose metabolism
Metabolism
- The total of all cellular reactions that occur in cells and includes chemical pathways that results in synthesis of molecules as well as breakdown of molecules
Mitochondrion
- The subcellular organelle responsible for the production of ATP with oxygen
- Contains enzymes for the Krebs cycle electron transport chain and the fatty acid cycle
Molecular biology
- branch of biochemistry Involved with the study of gene structure and function
Nicotinamide adenine dinucleotide (NAD+)
- Coenzyme that transfers hydrogen and the energy associated with those hydrogens
- in krebs: NAD transfers energy from substrates to the electron transport chain

Nucleus
- membrane-bound organelle containing most of the cells DNA
Organic
- describe substances that contain carbon
Oxidation
- removal of electrons from an element of molecule
Oxidative phosphorylation
- mitochondrial process in which energetic phosphate is couple to EDP as energy as transferred along the electron transport chain in which oxygen is a final electronic acceptor
Phosphocreatine (PC)
- Compounds found in skeletal muscle and use to resynthesize ATP from ADP
Phosphofructokonase (PFK)
- rate limiting enzyme in glycolysis that is responsive to ADP, Pi, And ATP levels in the cytoplasm of the cell
Reduction
- gain of electrons
The oxidation of acetyl-CoA results in what?
- The production of carbon dioxide and ATP