Bioenergetics and Biological Oxidation Flashcards
Outline the two thermodynamic properties of a reaction
The free energy difference (∆G) between the products and reactant, which determines whether the reaction will be spontaneous
The energy required to initiate the conversion of reactants to products determines the rate of the reaction.
……… is a measure of the change in randomness or disorder of reactants and products
∆S, Entropy
What is enthalpy
It a measure of the change in heat content of the reactant and product. (∆H = E +PV)
At equilibrium, ΔG = ?
0
State the change in free energy of a biochemical process according to the second law of thermodynamics
∆G = ∆H - T∆S
A reaction can occur spontaneously only if ∆G is ……
negative
What is an exergonic reaction?
One that is accompanied by the release of energy.
If if ΔG is positive, the reaction is termed ………
Endergonic
Why are can’t endergonic reactions occur spontaneously?
An input of free energy is required to drive such a reaction
What is ATP composed of?
ATP consists of a molecule of adenosine to which three phosphate groups are attached.
adenine + ribose = ?
adenosine
The ∆G◦ of hydrolysis of ATP, is approximately ………. for each of the terminal phosphate groups
-7300 cal/mol
How does creatine kinase catalyse the rapid replenishment of ATP?
through transfer of the activated phosphoryl group from phosphocreatine to ADP
the reactions of catabolism lead to the …………. of ATP
synthesis
Anabolic reactions, as well as the other reactions involved in cellular maintenance, use ………….. to drive the reactions.
the coupled hydrolysis of ATP
