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Biochemistry > Biochemistry of the LIver > Flashcards

Biochemistry of the LIver Flashcards

1
Q

Name the plasma proteins from smallest to largestq

A

Albumin
Alpha globulins
beta globulins
gamma globulins

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2
Q

Give two example of alpha globulins

A

ceruloplasmin

retinol binding protein

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3
Q

what does retinol binding protein transport

A

vitamen A

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4
Q

name two beta globulins

A

transferrin

fibrinogen

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5
Q

what does transferrin transport

A

iron

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6
Q

what is fibrinogen

A

inactive form of fibrin

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7
Q

what is the most abundant plasma protein

A

albumin

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8
Q

what plasma protein is the main determinent of oncotic pressur

A

albumin

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9
Q

what stimulates albumin production

A

insulin

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10
Q

how is iron stored in cells

A

as ferritin

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11
Q

what plasma protein transports copper

A

ceruloplasmin

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12
Q

what vitamins are stored in the liver

A

A
D
B12

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13
Q

what is cholesterol an important precursor for

A

bile acids
steriods
vitamin D

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14
Q

what is required to synthesize cholesterol

A

acteyl coA
NADPH
ATP

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15
Q

what is the rate limiting enzyme in cholesterol synthesis

A

HMG coA reductase

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16
Q

What does HMG coA reductase synthesis

A

mevalonic acid

17
Q

Name the steroids produced from cholesterol

A

corticosteroids - adrenal cortex
androgens- testis
estrogens- ovary

18
Q

what enzyme catalyses the first step of metabolism in the liver

A

cytochrom p-450 oxidases

19
Q

what is bilirubin conjugated with

A

glucuronic acid

20
Q

what is bilitrubil catabolised to in the liver

A

sterocobilinogen (colourless)

21
Q

what is bilirubin oxidised to

A

stercobilin (coloured)

22
Q

where is excess glucose diverted to

A

the pentose phosphate pathway

23
Q

what does the pentose phosphate pathway do

A

makes NADPH

Biochemistry (4 decks)

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