Biochemistry - DNA Flashcards
1
Q
What is the central dogma?
A
flow of information from DNA towards protein
2
Q
Difference between the structure of ribose and 2-deoxyribose
A
No hydroxyl group on 2nd carbon of 2-deoxyribose but it is present in ribose
3
Q
What is a nucleoside and a nucleotide?
A
Nucleoside = base + sugar
Nucleotide = nucleoside + phosphate group(s)
4
Q
For each base, write the name when combined with a sugar
A
adenosine
cytidine
guanosine
thymidine
uridine
5
Q
Where in DNA does a phosphodiester bond form?
A
between the a free 3’ OH group and a 5’ triphosphate
6
Q
What is required to start DNA replication?
A
A RNA primer which is synthesised by primase
7
Q
What is the direction for the leading and lagging strand?
A
leading = 3’ to 5’
lagging = 5’ to 3’
