BIOCHEMICALLY IMPORTANT ENZYMES Flashcards
considered a specific marker for liver disease
SGPT
present in liver tissue, and elevations may be seen in liver disease such as hepatitis and cirrhosis
LDH4 AND LDH5
an enzyme that is found primarily in skeletal and cardiac muscle and in
smaller fractions in the brain
CREATINE KINASE
found in the liver
SGOT
useful in the diagnosis of myocardial infarction
LDH1 AND LDH2
TYPES OF CK
muscle (CK-MM)
brain (CK-BB)
cardiac tissue (CK-MB)
present in the heart, kidney, pancreas, lungs, and skeletal muscle
SGOT
enzyme that aids in the digestion of fat
LIPASE
important marker in the diagnosis of acute myocardial
infarction
cardiac tissue (CK-MB)
For diagnosis of liver disease
SGOT
primarily secreted by the pancreas
LIPASE
sensitive markers of cardiac injury
Troponin I and T
useful in the diagnosis of pancreatitis
LIPASE
enzyme found in the liver, kidney, and pancreas
g-Glutamyl Transpeptidase
found solely in the cardiac muscle
TROPONIN I
GGT MEANING
g-Glutamyl Transpeptidase
considered a more specific marker
for acute pancreatitis than amylase
LIPASE
found in both cardiac and skeletal muscle
Troponin T
useful in the diagnosis and monitoring of alcoholic liver disease
GGT
enzyme that aids in digestion by breaking down complex carbohydrates into simple sugars
AMYLASE
GASTROINTESTINAL TESTS
- Alanine Aminotransferase/ serum glutamic pyruvic transaminase (SGPT)
- Aspartate Aminotransferase/ serum glutamic oxaloacetic transaminase (SGOT)
- g-Glutamyl Transpeptidase
-Lactate Dehydrogenase
-Lipase
-Amylase
Increased GGT may be seen in these diseases
alcoholic liver disease
metastatic liver disease
obstructive jaundice
cholelithiasis
pancreatitis
liver tissue
SGPT
produced in the pancreas and salivary glands, and lesser amounts are secreted by the fallopian tubes, lungs, thyroid, and tonsils
AMYLASE
enzyme involved in the interconversion of lactate and pyruvate
Lactate Dehydrogenase
most often used in the diagnosis of acute pancreatitis
SERUM AMYLASE
located in myocardial, muscle, and renal tissue
SGPT
found in many tissues, including heart, brain, liver, skeletal muscle, kidneys,
lungs, and RBCs
Lactate Dehydrogenase
SGPT MEANING
serum glutamic pyruvic transaminase
SGOT MEANING
serum glutamic oxaloacetic transaminase