biochem in cell Flashcards

1
Q

“everything that living
things do can be
understood in terms of
the jigglings and
wigglings of atoms”

A

Richard Feynman
- Sperm fertilizing an
egg.

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2
Q

“Living things are composed of lifeless molecules”

A

Albert Lehninger

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3
Q

“Chemistry is the logic of biological phenomena”

A

Garrett and Grisham

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4
Q

complicated and highly organized

A

Living Organisms

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5
Q

serve functional purposes

A

Biological structures

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6
Q

actively engaged in energy
transformations

A

Living systems

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7
Q

have a remarkable capacity for self-
replication

A

Living systems

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8
Q

flows from photosynthetic organisms through
food chains to herbivores and on to carnivores at the apex of
the food pyramid

A

Solar energy

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9
Q

1st primary Producers

A

photosynthesis

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10
Q

1st primary Consumers

A

herbivores

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11
Q

2nd primary Consumers

A

Carnivores

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12
Q

Organisms capture energy in the form of special
energized molecules

A

ATP, NADPH

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13
Q

ATP structure draw

A

drawing

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14
Q

NADPH structure draw

A

drawing

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15
Q

Two complementary
polynucleotide chains running in opposite directions can pair
through hydrogen bonding between their nitrogenous bases.
Their complementary nucleotide sequences give rise to
structural complementarity.

A

DNA double helix

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16
Q

DNA double helix

A

5’ top
3’ bottom

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17
Q

Covalent bond
formation by e- pair sharing
makes _____ appropriate
for the support of life

A

H, O, C and N

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18
Q

make up 99+% of atoms in the human body

A

H, O, C and N

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20
Q

63% atoms in the human body

A

Hydrogen

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20
Q

25.5% atoms in the human body

A

Oxygen

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21
Q

9.5% atoms in the human body

A

Carbon

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22
Q

1.4% atoms in the human body

A

Nitrogen

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23
Q

What property unites H, O, C and N and renders
these atoms so appropriate to the chemistry of life?

A

ability to form covalent bonds by
electron-pair sharing

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24
Q

H-H bond

A

436 kJ/mol

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25
Q

C-H bond

A

414 kJ/mol

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26
Q

C-C bond

A

343 kJ/mol

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27
Q

C-O bond

A

351 kJ/mol

28
Q

formation by e-
pair sharing

A

Covalent bond

29
Q

the Units for
Building Complex Structures

A

Simple Molecules

30
Q

example of linear aliphatic

A

stearic acid

31
Q

example of cyclic

A

cholesterol

32
Q

example of branched

A

B-carotene

33
Q

example of planar

A

chlorophyll a

34
Q

inorganic precursors: (16-64 daltons)

A

carbon dioxide

35
Q

metabolites: (50-520 daltons)

A

pyruvate

36
Q

building blocks: (100-350 daltons)

A

alanine (amino acid)

37
Q

macromolecules: (10^3 - 10^9 daltons)

A

protein

38
Q

have a
“sense” or directionality

A

Macromolecules and their building blocks

39
Q

informational

A

Macromolecules

40
Q

have characteristic three-dimensional
architecture

A

Biomolecules

41
Q

maintain biological structure and
determine biomolecular interactions

A

weak forces

42
Q

build proteins

A

Amino acids

43
Q

are built by joining sugars
together

A

Polysaccharides

44
Q

polymers of nucleotides

A

Nucleic acids

45
Q

hold atoms together so that
molecules are formed

A

Covalent bonds

46
Q

profoundly influence the structures
and behaviors of all biological molecules

A

Weak forces

47
Q

create interactions that are constantly
forming and breaking under physiological
conditions

A

Weak forces

48
Q

Energies of weak forces range from

A

0.4 to 30 kJ/mol

49
Q

weak forces include

A
  • van der Waals interactions
  • Hydrogen bonds
  • ionic interactions
50
Q

Van der Waals Interactions

A

0.4-4.0 kJ/mol

51
Q

Hydrogen Bonds

A

12-30 kJ/mol

52
Q

Ionic Interactions

A

20 kJ/mol

53
Q

Hydrophobic Interactions

A

<40 kJ/mol

54
Q

mediated by weak
chemical forces

A

Biomolecular recognition

55
Q

restrict organisms to a narrow range of
environmental conditions

A

weak forces

56
Q

contribute to
the stability of
proteins

A

Ionic bonds

57
Q

the principle that guides the
biomolecular interactions that characterize the
living state.

A

Molecular Recognition Through Structural
Complementarity

58
Q
  • A single (plasma) membrane
  • No nucleus or organelles
A

Prokaryotic cells

59
Q
  • Much larger in size than prokaryotes
  • 103-104 times larger!
  • Nucleus plus many organelles
  • ER, Golgi, mitochondria, etc.
A

Eukaryotic cells

60
Q

a member of the
coliform group of bacteria that colonize the intestinal tract of
humans.

A

Escherichia coli or Ecoli

61
Q

genetic elements enclosed in a protein
coat.

A

viruses

62
Q

not free-living organisms and can reproduce
only within cells.

A

viruses

63
Q

how an almost absolute specificity
for their particular host cells, infecting and multiplying only
within those cells.

A

viruses

64
Q

known for virtually every kind of cell.

A

viruses

65
Q

mobile bits of
genetic information encapsulated in a protein coat.

A

viruses