Biochem Flashcards
Oxidation of Amine into Quinone
Teuber Reaction
arginine yields Citrulline and Ornithine, N-acetyl glutamate, Three ATP yields 2ADP 1AMP, fumate, OTCD, CSP-I
Krebs-Henseleite Urea Cycle
Ehlers-Dalos, Alport’s Syndrome, glycine is 1/3 of it, Lysyl Oxidase,
Collagen
discovered by Jens Skou, Cardiac Glycosides i.e Ouabain and Digoxin inhibit this protein leading to buildup of Calcium and stronger heart contractions, FXYD, Uses a fuck load of ATP.
Sodium-Potassium Pump
Precursor to melanin, L-DOPA, A-A-A-H hyroxylates phenylalanine to make this amino acid, SH2 allows Kinases to bind to it,
Tyrosine
activate STAT transcription factors
JAK (Janus Kinases)
C-SRC causes chicken cancer, Peyton Rous, encoded by a proto-oncagone
SRC (pronounced “Sarc”)
Ras activates Map cascade, have SH2 domains, add phosphate groups to proteins
Kinases
Foam Cells, HMG CoA reductase, SREPB, Squalene, Mevalonate
Cholesterol
Leading protein cause of Cancer :O, activates MAPK cascade, P loop, GAP, GEF, proto-oncogone
Ras
Weiss units, T4 bacteriophage, XRCC1
Ligase
Subtilisin cleaves this protein to form a Klenow fragment, PCNA clamps to this, Arthur Kornberg
DNA Polymerase
codes for TRNA’s, Inherited from mother, Twinkle helicase
Mitochondrial DNA
INO80, SWI, NURD (remodeling), 30nm fiber, “beads on a string”, wrap around the bromodomains of histones, hetero version stains more dark
Chromatin
“twist” and “writhe” linking number, purified by QIAgen spin column, Cpg sites get methylated
Just DNA
