Biochem 2 exam - leys

Question 1

Through what 2 processes do cells acquire nucleotides?

Answer 1

1) de novo synthesis

2) salvage pathways

Question 2

What does de novo synthesis of purines result in?

Answer 2

It results in the synthesis of inosine that can be converted into adenosine and guanosine.

Question 3

Where are atoms in a newly synthesized purine derived from?

Answer 3

are derived from several sources including amino acids aspartame, glutamine and glycine, methyl group supplied by folic acid and carbon dioxide.

Question 4

What regulates de novo synthesis of purine at multiple points in the pathway?

Answer 4

ADP and GDP