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Biochem; Re 2 > †Biochem 1 > Flashcards

†Biochem 1 Flashcards

1
Q

barbiturates inhibit which component of ETC

A

NADH dehydrogenase
(Complex I)

“BPAR”

Barbiturates
Piericidin A
Amytal
Rotenone

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2
Q

osteogenesis imperfecta’ defect

A

GLYCOSYLATION

Glycosylation of pro-α-chain hydroxylysine residues and formation of procollagen via hydrogen and disulfide bonds

problem involving triple helix formation leads to osteogenesis imperfecta

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3
Q

is bradykinin octapeptide or nonapeptide?

A

NONAPEPTIDE

  • Vasopressin
  • Oxytocin
  • Bradykinin
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4
Q

best described as being trans-acting

A

Repressor

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5
Q

glycerophospholipid that functions to signal apoptosis

A

phosphatidylserine

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6
Q

test for Vit B12

A

Schilling test

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7
Q

enzyme deficient in Type 1 galactosemia

A

Galactose 1-phosphate uridyltransferase

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8
Q

pyruvate to ethanol

A

pyruvate decarboxylase

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9
Q

remarks on gluconeogenesis

A

gluconeogenesis from pyruvate requires oxidation of 2 NADH

cleavage of 6 high-energy phosphate bonds (4ATP, 2 GTP)

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10
Q

substitution of purine to pyrimidine is what kind of mutation

A

transversion

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11
Q

remarks on fibronectin

A

involved mainly in cell adhesion and signaling

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12
Q

cystinuria: defect of renal tubular amino acid transporter in ______ for the following amino acids:

A

PCT

“COLA”

Cystine
Ornithine
LYSINE
ARGININE

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13
Q

IEOM with increased risk for liver cancer

A

TYROSINEMIA TYPE I

-cobbage-like odor

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14
Q

treated with large doses of fat soluble vitamins, particularly vitamin E

A

abetalipoproteinemia

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15
Q

part of lactose operon that encodes for thiogalactoside transacetylase

A

A gene

i: lac repressor protein
Y: galactoside permease
Z: beta galactosidase

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16
Q

liporprotein with highest triacylglycerol content

A

chylomicrons

17
Q

most abundant GAG in the body

A

Chondroitin sulfate

-found in cartilage, bone, CNS

Biochem; Re 2 (3 decks)

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