BIOC amino acids Flashcards

1
Q

What amino acids are very non-polar?

A

A, V, L, I, M, F
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2
Q

What amino acids are moderately non-polar?

A

C, G, P, W, Y
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3
Q

What amino acids are polar uncharged?

A

S, Q, N, T
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4
Q

Which amino acids are hydrogen bond acceptors and donors (accept and donate electrons) at pH 7?

A

Q, H, S, T, Y, N
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5
Q

What amino acids are polar positively charged?

A

H, K, R

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6
Q

Which amino acids are only hydrogen bond acceptors at pH 7?

A

D, E

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6
Q

What are the hydrophobic AA?

A

Y, A, P, I, L, M, F, W, V

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6
Q

What amino acids are polar negatively charged?

A

D, E

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6
Q

What are the hydrophilic AA?

A

K, R, N, Q, E, D,
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7
Q

Which amino acids are only hydrogen bond donors at pH 7?

A

R,K,W

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8
Q

Which AA favour the alpha-helix?

A

Ala, Arg, Gln, Glu, His, Leu, Lys, Met, (Phe)

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8
Q

What are the neutral AA?

A

Tyr, Thr, Ser, Pro, His, Gly

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9
Q

pH<pKa

A

protonated

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9
Q

Which AA have a charge of 0 when protonated, -1 when deprotonated?

A

D, E, Y, C, C-ter.

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10
Q

Which AA have a charge of +1 when protonated, 0 when deprotonated?

A

R, H, K, N-ter.

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11
Q

pH>pKa

A

deprotonated

11
Q

Which AA favour the beta-sheet?

A

Trp, Tyr, Val, Ile, Thr, Cys, (Phe)

12
Q

pH=pKa

A

50/50 protonated/deprotonated

13
Q

What are the secondary structure breakers?

A

GPNDS (2-3, in a run with 4 AA)

13
Q

Describe the B-sheet structures?

A

Big: W, Y, (F)
branch on B-carbon: V, I, T
S on B-carbon: C