Bio Ch 8 Flashcards
Telomeres
sections of noncoding, repetitive DNA that acts as a protective cap on the tip of each chromosome
- eventually run out of telomeres
- results in death of cells
- association between length of telomeres and aging
- newborn baby has very long telomeres
—your cells aren’t immortal; mortality to cells
Hutchinson-Gilford progeria
Telomeres are shorter than normal. Begin to appear aged early after birth. Rarely live past age 13
Some cells rebuild their telomeres
-single-celled eukaryotes
-cells that produce gametes
Cancer
telomere rebuilding and uncontrolled cell division
Normal cell division is necessary
to maintain most organisms
In eukaryotic cells, telomeres…
keep track of cell divisions by shortening every time the cell divides
If the telomere becomes too short
= additional cell divisions after will cause loss of essential DNA and cause cell death
How many chromosomes in sperm/egg cell
sperm cell= 23 unpaired chromosomes
egg cell= 23 unpaired chromosomes
Total= 46 chromosomes in fertilized egg (because they combine)
Prokaryotic cells
single circular chromosome attached to cell membrane
Eukaryotic cells contain
linear chromosomes within a nucleus
Binary Fission
-replication: cell creates a duplicate of each chromosome
- parent cell divides to create 2 daughter cells
—–cell elongates and pinches into 2
-Prokaryotic cell division= Binary Fission
-Asexual Reproduction
Interphase
Gap 1: cells primary growth phase. Normal cellular functions take place
S phase: preps for cell division. Replication occurs here
Gap 2: 2nd period of growth
G0: some cells never divide
ex: the brain (doesn’t make new cells)
- resting phase outside of cell cycle
-cells may stay here for days or years
After Interphase comes
Mitosis: parent cell’s nucleus with it’s duplicated chromosomes divide
Cytokinesis: cytoplasm divides into 2 identical daughter cells
Cell Cycle Control System
3 primary checkpoints that regulate cell cycle in eukaryotes
G1/S Checkpoint
G2/M Checkpoint
Spindle Assembly Checkpoint
G1/S Checkpoint
is DNA damaged?
does cell have sufficient nutrients?
-make past this; DNA then replicates