bio 252 Flashcards

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1
Q

4 types of intercellular communication

A
  1. gap junctions through cytoplasm
  2. neurotransmitters through synaptic cleft
  3. paracrines through interstitial fluid
  4. hormomes through the blood
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2
Q

what are hormones traveling through blood important?

A

They illicit a systemic response, cell to cell communication, travel great distance.

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3
Q

principles of hormone communication

A
  1. hormones are released by endocrine glands (endocrine cells, neuroendocrine glands)
  2. Picked up by blood
  3. hormones travel throughout the body
  4. hormones “diffuse” out of the capillaries
  5. hormones stimulate “target cells”
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4
Q

what is different about target cell capillary in hormone communication

A

target cell capillaries are fenestrated, basically look like windows where the hormone comes in. more surface area.

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5
Q

endocrine system and communication

A
  1. communication by hormones
  2. releases hormones to blood
  3. potentially widespread effect
  4. slow response
  5. long lasting
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6
Q

what is a humeral stimulus?

A

where the hormone released in response to ion levels in the body, ex. parathyroid glands and calcium.

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7
Q

neural stimulus

A

hormone release caused by neural input.

ex would be CNS releasing preganglionic sympathetic fibers, to medulla of adrenal gland to release epi.

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8
Q

hormonal stimulus

A

a hormone release caused by another hormone (a tropic hormone). Ex. Anterior pituitary gland to release other hormones.

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9
Q

function of hypothalamus

A

located in the third ventricle of the brain, controls water balance, thermoregulation, sex drive, childbirth and various autonomic functions. many functions executed by pituitary gland.

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10
Q

how can hypothalamus exert control over pituitary gland.

A

nervous system signals and endocrine signals

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11
Q

why is the pituitary gland divided into two parts?

A

anterior parts communicates via hormones, posterior part communicates through nervous system.

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12
Q

the connection between hypothalamus and anterior pituitary gland?

A

vascular connection, still uses hormones but communication is through blood making it vascular. the system is called Hypothalamo-hypophyseal Portal System

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13
Q

ADH antidiuretic hormone

A

stimulus - high blood osmolarity
messenger- ADH
response- increase water retention
increase thirst

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14
Q

oxytocin

A

stimulus- neural stimulus (specifically during childbirth)
messenger- Oxytocin
response- smooth muscle contraction (uterus, reproductive ducts, and mammary glands) promotes emotional bonding.

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15
Q

anterior pituitary hormones released when stimulated by hypothalamic hormones / trophic because their role is release other hormones.

A
Gonadotropin- releasing hormone
Thyrotropin- releasing hormone
Corticotropin- releasing hormone 
Prolactin- inhibiting hormone
Growth hormone- releasing hormone
growth hormone- inhibiting hormone (somatostatin)
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16
Q

Anterior Pituitary gland exclusive hormones

A

FSH (follicle stimulating hormone) - stimulates secretion of ovarian sex hormones, development of ovarian follicles and sperm production.
LH (luteinizing hormone) - stimulated ovulation, stimulates corpus luteum to secrete progesterone & stimulates testes to secrete testosterone

17
Q

ACTH

A

Adrenocorticotropic hormone- stimulates adrenal cortex to secrete glucocorticoids

18
Q

PRL

A

Prolactin - afterbirth stimulates mammary glands to synthesize milk, enhances secretion of testosterone by testes.

19
Q

TSH

A

Thyroid Stimulation Hormone- stimulates secretion of thyroid hormone

20
Q

GH

A

Growth Hormone- stimulates mitosis and cellular differentiation.

21
Q
Growth Hormone (somatotropin) 
IGF - 1 (somatomedin)
A

sleep, exercise, low glucose, high protein, fasting between 12 to 16 hours, stress (good stress) like lifting
Direct (repairing tissue, bone, muscle, elevation of blood glucose & blood fatty acids) and indirect effects
(stimulating IGF *insulin growth factor) important mediator for growth in children to adolescence.

22
Q

GH & IGF cause our bodies to use…

A

fats for energy.. to avoid protein & glucose utilization for fuel preferred fuel
spare protein for repairs/growth…make proteins available for growth
and spare glucose…reduces use of carbs for glucose dependent organs bc of limited glycogen (glucose sparring effect) ex. like rbc’s, cns

23
Q

Lypolysis

A

Breakdown of fats into fatty acids for energy use

24
Q

Glycogenolysis

A

the breakdown of glycogen to produce glucose

25
Q

Gluconeogenesis

A

the use of fats/proteins to produce glucose

26
Q

Gigantism

A

GH hypersecretion during childhood or adolescence.

Epiphyseal plates are open and makes bones longer.

27
Q

Acromegaly

A

Post adolescent hypersecretion, thickening of bones & soft tissues epiphyseal plates are closed.

28
Q

Pituitary Dwarfism

A

GH hyposecretion - made rare since GH supplementation has become available