BIO 204 Flashcards
All terms!!!!!
Fact
Observation that is repeatedly confirmed.
Hypothesis
Statement about a natural phenomena that can be tested, then supported or denied.
Theory
Highly probable, well-tested explanation of a natural phenomena based on observations and experiments.
Scientific Method
Observation, question, hypotheses, empirical test, conclusion.
Evolution
Descent with modification.
Gregor Mendel
Founded the field of genetics.
Genetics
Explain how traits are passed from parent to offspring.
Chromosome
Single strand of DNA, 1000s of genes.
Gene
Information that codes for inherited traits. (Position of gene on chromosome = locus).
Genome
Collection of genetic information in a cell.
Chromosome Theory
Developed by Walter Sutton and Theodore Boveri. Recognizes the chromosems as genetic material.
How many chromosomes are in humans?
46 total chromosomes. (2 pairs of 23).
Gametes
1 set of chromosomes. (1n = haploid).
Somatic
All chromosomes except for gametes. (2n = diploid).
Polypeptide
Chain of amino acid.
Chromatin
DNA + protein (histone).
Deoxyribonucleic acid (DNA)
Directs cellular functions (protein synthesis) and contains hereditary material (genes).
3 MAIN PARTS:
1) nitrogenous bases - A, T, G, C
2) deoxyribose - sugar
3) phosphate - PO4
Nitrogenous Bases
T- thymine, A - adenine, C - cytosine, G - guanine
(T+A and C+G)
Chargaff’s Rule
Nucleotide base composition vary among species.
%A=%T and %G=%C
%A+%T+%G+%C=100%
Crick and Watson
Determined bouble helix structure of DNA using Rosalind Franklin’s DNA photo.
Gene expression
Process where DNA dictates proetin synthesis which leads to specific traits.
Phenotype
Observable trait. (eye color, hair color, etc.)
Genotype
Genetic code for phenotype.
Inherited DNA
Programs for synthesis of polypeptide that contribute to proteins.
Transcription
Making of RNA from DNA, takes place in eukaryotes.
Translation
Making of popypeptide protein from RNA, takes place in cytoplasm. Performed by RNA and ribosome. (U replaces T).
Codon
Triplet code of nucleotides to code one amino acid in mRNA. (ex. AAA, UAU, GCG)
3 letter words to make RNA language
Mutation
Changes to genetic code that are responsible for the production of new genes.
Allele
New mutated version of a gene.
Point mutation
Change of single nucleotide base.
2 types: subsitution (CAG –> CTG), insertion and deletion (CAG –> CAAG or CG)
Silent mutation
Change in genotype, no change in phenotype.
Missense mutation
Change in genotype leading to a change in the amino acid.
Nonsense mutation
Change in genotype that codes a stop codon –> nonfunctional protein as a result.
like a period in the middle of a sentence
Frameshift mutation
Insertions/deletions that throw off the triplet reading frame.
ex. AUG TAC CCA –> A UGT ACC CA
Modern definition of evolution
Change in allele frequency within a poplation from one generation to the next.
Uniformitarianism
Laws of chemisty and physics have remained the same thoughout all of Earth’s history.
the present is the key to the past
Jean-Baptiste Lamarck
Naturalist, argued inheritance of required characteristics.
HMS Beagle
Voyage Darwin went on to the Galapagos where he developed his theory of natural selection.
Natural selection
Heritable traits beneficial to survival are slected and become more common in a population.
Darwin’s Postulates (reworded)
- Mutations generate new genotypes phenotypic variation
- Individuals pass their genes to offspring heritable
- Some individuals with favorable phenotypes are more able to pass their genes to the next generation (“fitness”) adaptation increases fitness
- Individuals that survive have genotypes that code for phenotypes that best adapt them to the environment nonrandom
Fitness
Ability to survive in environment, determined by environment, quantifiable but relative among individuals.
Agents of natural selection
Predator/prey, competition for resources, disease and arasites, mating opputunities (sexual selection).
Mechanisms for change in allele frequency:
Mutation, migration, genetic drift, natural selection.
Genetic drift
Random sampling error over generations.