BIO-168-003 Flashcards
Epithelial tissue
Composed of one or more layers of tightly packed cells and it contains little to no extracellular matrix. Covers the body, lines cavities, and forms glands.
Connective tissue
Composed of cells, protein fibers, and ground substances.
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Muscle tissue
Consists of cells that are highly specialized for the active generation of force for contraction. Can elongate and change shape by becoming either shorter or thicker.
Nervous tissue
Composed of neurons and glial cells.
Subdivisions/Connective Tissue; loose connective tissue
Areolar, Adipose, Reticular
subdivision/connective tissue; Dense connective tissue
Dense Regular, Elastic, Dense irregular
Subdivision/connective tissue; supportive connective; cartilage
Hyaline, fibrocartilage, Elastic
Subdivision/connective tissue; Fluid connective tissue
Blood, lymph
Ectoderm
Epidermis, glands on skin, nervous system, skin cells, neurons
Mesoderm
Connective tissue, skeletal muscle, red blood cells, smooth muscle
Endoderm
lining the airway, and digestive system
Thick skin
Palms, hands, soles of the feet. No hair, 5 layers
Thin skin
Covers the body, 4 layers, sweat glands
Meissner’s corpuscle
fine touch
hair follicle receptor
crude touch
Merkel disc
light touch
Pacinian corpuscles
deep pressure, vibration, proprioception
Ruffini corpuscles
sensitive to stretching of skin
Free nerve ending
Pain and temperature
Hair
A keratinous filament
Nail Bed
Rich in blood vessels
Nail body
protects the tips of fingers/toes, back support
Lateral nail fold
Anchors the nail body
Sebaceous gland
oil gland found everywhere, waterproofs skin and hair
Skin cancer
An accumulation of DNA mutations
Basal cell
epidermis, most common
Squamous cell
Middle-outer layers of skin
melanoma
Highly metastatic; develops in the cells
epidermis wound
cell regeneration
Dermal wound
Inflammatory, Migration, proliferation and maturation
5 functions of the nervous system
sensation, response, integration, homeostasis, mental
Central nervous system
Brain, spinal cord
Peripheral nervous
Ganglion, nerves
Astrocyte
CNS, blood-brain barrier, repair
Ependymal
CNS, cilia, makes cerebral spinal fluid
Schwann
PNS, forms on mylier, axons
microglia
CNS, phagocytosis of bacteria, debris immune cell
Oligodendrocyte
CNS, forms mylien on axon
Satellite
PNS, surrounds & protects neurons
Multipolar Neuron
Dendrites attached to their cell bodies, one long axon
Bipolar neuron
2 processes, not very common, one axiom and one dendrites, found in olfactory epithelium and ventricles
Unipolar neuron
One long axon from cell body, at one end of axon is the dentries, axon forms synaptic connection
Somatic
Responsible for conscious perception, voluntary motor responses
Automatic
Involuntary control
Resting potential
when ion channels are all closed
Depolarization
A shift in cell membrane charge, crucial for nerve signal transmission, muscle contraction
repolarization
The return of a cell membrane to its resting potential after depolarization
Hyperpolarization
Increase in the membrane potential of a cell, making it more negative than its resting potential after depolarization
refractory period
When the sodium-potassium pump “corrects” the location of NA+ and K+
Brainstem
A “tapering cone”, connects the brain to the spinal cord
Medulla oblongata
Regulates the cardiovascular and respiratory system
Pons
Bridge between the cerebellum & brainstem therefore highly involved in motor controls
diencephalon
Connection between the cerebrum& the rest of the nervous sytem
Hypothalamus
Involved in the regulation of homeostasis and regulation of the pituitary gland
pineal gland
Sleep/wake cycle
cerebellum
balance, movement, fine motor, muscle tone
frontal
language, planned movements
parietal
Includes all tactile senses
Temporal
Auditory, smell, memories
Occipital
Sight
Facial Nerve
Anterior part of tongue
Glossopharyngeal
Posterior part of tongue
Vagus
Extreme posterior part of tongue, gag reflex
Olfactory
smell
optic
seeing
auditory
Hearing
integration
processing of sensory information
Myelin sheath
Protective covering around nerve fibers
summation
Adding up signals in a neuron
synapse
Gap between nerve cells where they communicate by sending chemical/electral signals
Neurotransmitter
Chemical messenger
rods
Very sensitive to lights, cannot detect color, shades of gray, found primarily in peripheral vision, 120 million
Cones
color vision, 6-7 million, double layer disc w/ photopigments and photopsins
static
head position
Dymanic
head movement
Hyaline
Most bones develop from this, growth & repair, chondroblasts make cartilage matrix
Fibro
found between vertebral disc, joint capsules, ligaments
elastic
Found in external ear, larynx
osteoid
made by osteoblast, organic component, collagen
Matrix
A complex structure made of organic & inorganic components
diaphysis
Shaft of bone runs between distal and proximal ends of the bone
Epiphysis
Knobs at the end of the bone
metaphysis
growth zone
articular cartilage
a thin layer of hyaline over epiphysis
medulla cavity
contains yellow bone marrow in adult, hollow
periosteum
Dense irregular connective tissue covering bone where there is no cartiliage, location of blood vessels
Endosteum
Line the medullary cavity, growth repair remolding
osteogenic cells
stem cells, undifferentiated cells that become osteoblast
osteoblast
Immature bone cells that form bone matrix, becomes trapped in matrix and becomes osteocytes
osetocytes
Maure osteoblast cells; live in lacunae
Osteoclast
degrade bone to initiate bone remolding
chondroblast
produce matrix of cartilage
Long bones
Longer than wide, movement and support
short bones
Long as wide, provide support and little movement
Irregular bones
varying in size
flat bones
thin, curved, protect internal organs
sesamoid bones
small, round, forms in tendons
Endochondral Ossification: step 1
Cartilage model of the future bone is formed
Endochondral Ossification: step 2
Cartilage grows and gets surrounded by membrane which will become the future periosteum
Endochondral Ossification: step 3
Blood vessel invade cartilage, bringing osteoblast that replace cartilage with spongy bone at the primary ossification center
Endochondral Ossification: step 4
Appear in the epiphyses of bone, forms spongy bone
Endochondral ossification: step 5
The epiphyseal plate allows of lengthwise growth of the bone while the cartilage is replaced by bone
Endochondral ossification: step 6
Eventually, the epiphyseal plate closes, and all cartilage is replaced by bone, resulting in a mature bone
steps in bone repair:step 1
6-8 after a fracture hematoma is formed
steps in bone repair: steps 2
cells within hematoma develop into fibroblast, which makes collagen. Collagen forms a soft callus to stabilize the facture bone
steps in bone repair: step 3
The fibrocartilaginous callus is slowly replaced by stronger bony callus, made by spongy bone, created by osteoblast
steps in bone repair: step 4
Osteoclasts remove excess bony tissue, restoring the bone’s strength/shape
Fascia
Broad tendon
sarcolemma
Cell membrane of muscle fiber
T-tubules
Indentations of sarcolemma, penetrate the fibers, brings membrane close to SR; forms a trad
muscle fatigue
The inability of a muscle to contract in response to the nervous system signals
muscle relaxtion
Occurs when the nerve impulse stops
tetany
Involuntary contraction of muscles that lead to pain
muscle tension
The force generated when a skeletal muscle is stimulated to contact
Isometric Contraction
when the skeletal muscle tension is insufficient to overcome resistance
muscle tone
partially contracted, helps humans stay up right and move
Skeletal muscle
Multi-nucleated, long, cylindrical, striated, voluntary; attached to bones
cardiac muscle
Branching fibers that connect, intercalated disks, 1 or 2 nuclei, only found in the heart, striated and involuntary
Smooth muscle
Single nucleus, spindle-shaped fibers, non-striated muscle fibers
sarcomere
Basic functional unit of striated muscle fibers
myosin
arrange themselves to create thick filament
actin
need for movement for contraction, sliding mechanism that lets muscles to contract and relax
events at NMJ: step 1
Nerve impulse reaches NMJ
events at NMJ: step 2
voltage -gated calcium channels open, calcium moves into cell
events at NMJ: steps 3
Acetylcholine released into synaptic cleft
events at NMJ: steps 4
ACH diffuses across left
events at NMJ: steps 5
Ach binds to receptors on motor end plate
events at NMJ: step 6
ligand-gated na+ channels open na+ and diffuses into the muscle fibers
events at NMJ: step 7
depolarization of muscle fibers
events at NMJ: step 8
Action potential rapidly spreads along entire membrane
events at NMJ: step 9
membrane repolarizes resting membrane potential is restablished
events at NMJ: step 10
acetylcholinesterase removes ach form cleft receptors and recycles its components be used again
Description of sliding filament model
Thin filaments are pulled past thick filaments. myofilament does not change length during muscle contraction, they slide over. Sliding only occurs when myosin-binding sites are exposed and calcium is present. During contraction actin filaments move forward to the center of the sarcomere, the sarcomere shortens.
muscle contraction steps: step 1
Atp binds to each myosin
muscle contraction steps: step 2
transfers phosphate
muscle contraction steps: step 3
action potential travels down the sarcolemma
muscle contraction steps: step 4
Ca+ releases channels open in SR
muscle contraction steps: step 5
ca+ binds to troponin
muscle contraction steps: step 6
Tropomyosin moves off the myosin binding site on the actin
muscle contraction steps: step 7
myosin molecules change shape- power stroke pulls actin filament towards h-zone
muscle contraction steps: step 8
Atp binds to the myosin
muscle contraction steps: step 9
Myosin head detaches form actin & returns to cocked position and process start all over again
glycosis
Breakdown of glucose in cytosol of the cell
Creatine phosphate
a molecule with a high energy chemical bond, helps regenerate atp
aerobic cellular respiration
glycolysis in the presence of oxygen allows for pyrate to continue to be broken down in the mitochondria with additional production of atp
hypertrpohy
an increase in size of muscles, due to increase in myofibrils
Atrophied
Decrease in muscle size, Structal proteins are lost and muscle mass decrease
myoglobin
A molecule unique to muscle tissue, provides an extra source of oxygen for muscles
hemoglobin
found in red blood cells, releases oxygen when needecd