Bile Ducts Flashcards
Intrahepatic duct dilatation
CHD
RHD
LHD
Extrahepatic duct dilatation includes:
Cystic duct
CBD
Risk factors for biliary dilatation
Mirizzi syndrome
Choledocholithiasis
Cholangiocarcinoma
Mets
Clinical Presentation of biliary dilatation
RUQ pain
Jaundice
Elevated LFTS
Double barrel shotgun sign
AKA parallel channel sign
Dilated intrahepatic ducts adjacent to normal portal vein
Flashlight sign
Peripheral anechoic areas in liver that cause acoustic enhancement
anechoic tubular structure in liver that has antler or stellate branching pattern converging near porta hepatis
Sonographic sign of biliary dilatation
Dilated CBD
> =8 mm
Dilated CHD
> 5mm
What occurs when dilatation of biliary tree progresses?
Portal system becomes flattened
Normal CBD for adults older than 60
Add 1 mm to normal for each decade over
Ex: 80 years will measure 8 mm
Normal CBD for neonates
<1mm
Normal CBD for infants to 1 year
<2 mm
Normal CBD for older children (2-10)
<4 mm
Choledocholithiasis
Complete/partial obstruction of bile ducts by stones
Incidence of Choledocholithiasis
Greatest at time of cholecystectomy
3-4% of post cholecystectomy PTs
Ductal stones found in 75% of chronic bile duct obstructions
Risk factors for Choledocholithiasis
Cholelithiasis Sclerosing cholangitis Caroli’s disease Parasitic infection of liver Chronic hemolytic diseases Prior biliary surgery
Clinical presentation of Choledocholithiasis
Biliary colic
Jaundice
Elevated ALP, direct bilirubin, AST and ALT
Sonographic findings of Choledocholithiasis
Hyperechoic shadowing foci within CBD that MUST be demonstrated in orthogonal views
Structures that appear similar to Choledocholithiasis
Air or stool in adjacent bowel RHA crossing CHD and indenting it Refraction of beam Post op cholecystectomy clips Cystic duct impression on CBD Pneumobilia Mucous plug Calcification in pancreas head
Cholangitis
Inflammation of bile duct walls
Types of cholangitis
Acute bacterial
Recurrent pyogenic
HIV cholangiopathy
sclerosing
Incidence of recurrent pyogenic cholangitis
Affects male and female with equal frequency
Incidence of primary sclerosing cholangitis
Affects males more frequently than females (7:3)
Majority older than 45 years of age for cholangitis
T/F
False, less than 45 years old
What is the Charcot triad?
Fever, chills, and jaundice
Lab findings with cholangitis
Marked elevation of bilirubin and ALP with sclerosing cholangitis
Increased AST and ALT
Elevated WBC
Differential Diagnoses for cholangitis
Biliary obstruction
Caroli’s disease
Infection of ascariasis lumbricoides incidence
More frequent in children due to poor hygiene
More frequent in southern and gulf coast states in US
Most prevalent in Africa, Asia, and South America
Sonographic findings for cholangitis may include:
Thickening of bile duct walls with mild dilatation
Brightly echogenic portal triad
Thickened GB wall
Dilated ducts as large as 3-4cm
Sludge or pus in ducts
Dilatation of extrahepatic ducts packed with stones
Hydropic GB in 30% of cases
Pneumobilia
Hepatic abscess
Portal hypertension with liver damage and cirrhosis changes
Hemobilia
Blood in biliary tree
Hemobilia causes
65% caused by percutaneous biliary procedures and liver biopsies Infection Vascular malformation Trauma Malignancy
Blood and thrombus common in gallbladder with Hemobilia
T/F
True
Pneumobilia
Air in biliary tree
Risk factors for Pneumobilia
Incompetent sphincter of Oddi Post sphincter of Oddie sphincterotomy Gallstone ileus Emphysematous cholecystitis Trauma Duodenal ulcer perforating into CBD Post op Post ERCP
Sonographic findings of Pneumobilia
Hyperechoic collections of “dirty” shadowing within extrahepatic biliary ducts or GB
Cholangiocarcinoma
Primary cancer of the biliary ducts
Typically Adenocarcinoma arising from epithelial layer
Cholangiocarcinoma incidence
1/3 of all malignancies in liver
More common in males
50-60 years
Location of tumors: 1) CBD (esp. distal), 2) hepatic ducts, 3) cystic duct
Risk factors for cholangiocarcinoma
Primary sclerosing cholangitis Cholangitis Chronic biliary stasis Caroli’s disease Choledochal cysts Pancreatitis Ulcerative colitis
Hilar cholangiocarcinoma
Klatskins tumor
Types of cholangiocarcinoma
Intrahepatic
Hilar
Distal
Extrahepatic
Lab findings for cholangiocarcinoma
Elevated ALP and bilirubin
Diff Dx for cholangiocarcinoma
small pancreatic or ampullary carcinoma
Lymphadenopathy
Sonographic findings of cholangiocarcinoma
Normal pancreas, marked biliary obstruction
Mass involving bile duct
Echogenic bands across lumen
Hepatomegaly and ascites
Biliary atresia
Fibrotic obliteration of biliary tree
Biliary atresia most commonly affects:
Extrahepatic ducts
Incidence of biliary atresia
Neonates
Males (2:1)
Rare
Differentiating biliary atresia from ________________ is critical and difficult.
Neonatal hepatitis
Triangular cord
Sclerotic ductal remnant visualized at porta hepatis
Two signs that are pathognomonic for biliary atresia in a fasting infant
Triangular cord and small GB
What is the Kasai procedure?
Portoenterostomy
Roux-en-Y procedure
Choledochojejunostomy
Caroli’s disease
Congenital communicating cavernous ectasia of intrahepatic bile ducts
Incidence of Caroli’s disease
Affects males and females equally
Typically identified in childhood through 20’s
Sonographic findings in Caroli’s disease
Multiple cystic structures within liver that communicate with biliary tree
Stones and sludge may be seen in dilated ducts
Doppler of cystic structures demonstrated absence of flow
Central dot sign
Choledochal cysts
Congenital focal or diffuse cystic dilation of extrahepatic biliary tree
Incidence of Choledochal cyst
More common in East Asian populations
More common in females (4:1)
Typically identified in kids less than 10 yrs of age
Large, cystic mass in porta hepatitis separate from GB measures:
2-15cm