Beta Lactams

Question 1

Penicillin Classes

Answer 1

1) Natural Penicillins
-Penicillin G: Benzathine
-Penicillin VK
2) Aminopenicillins
-Amipcillin (IV),
Ampicillin/sulbactam (unasyn)
-Amoxicillin, Amoxicillin/Clavulanic Acid (Augmentin)
3) Extended Spectrum PCNs
-Piperacillin (Pipracil)
-Piperacillin/Tazobactam
(zosyn)
4) Narrow Spectrum PCNs
-Naficillin
-Oxacillin
-Cloxacilin
-Dicloxacillin

Question 2

Pen G

Benzathine

Answer 2

Route: Injectable, IM/IV
Benzathine IM only
IND: Benzathine=1st line for psyphilis, Strep, MSSA, Endocarditis, rheumatic fever (prophylactic), Lyme disease (2nd line)

MOA: Salt forms help with absorption; delayed absorption for longer time in tissues

ADR: pencillins + candidiasis

Question 3

Pen VK

Answer 3

Route: Oral
IND: Strep, MSSA, syphilis, enterococcus, rheumatic fever,