Beta-Blockers Flashcards
if patient is taking BB, but finding it difficult to deal with S/E such as bradycardia and cold extremities, what alternative drug choice would you recommend?
Oxprenolol, Pindolol, Acebutolol, Celoprolol
Which drugs are water soluble and why are these beneficial?
Atenolol,
Celiprolol
Nadolol
Sotalol
Beneficial: don’t cross the blood brain barrier and less likely to cause nightmares, excreted by the kidneys
Which drugs have longer duration and only need to be taken once daily?
Atenolol, bisoprolol, Nadolol
Which drugs are cardio-selective?
Atenolol, bisoprolol, metoprolol, Nebviolol, acebutolol
Which patients would need cardio-selective drugs?
Asthmatic or COPD patients
Name a non-cardioselective BB?
Sotalol
Which BB reduce mortality in patients who have had a MI?
Atenolol, metoprolol, propanolol
Which BB’s reduce morality in HF patients?
bisoprolol, carvedilol, nebivolol for stable mild-moderate HF in >70 years
Which BB is used for anxiety?
Propranolol
What are S/E of BB’s?
Fatigue
Coldness of extremities
Sleep disturbances with nightmares
Can affect carbohydrate metabolism causing hypo/hyperglycaemia in patients with or without diabetes
Whats the problem with BB and diabetics?
can mask the hypoglycaemia effect
How do BB’s work?
decrease cardiac output by altering baroreceptor reflex sensitivity and blocking peripheral adrenoreceptors
Which conditions are BB’s contraindicated in?
Uncontrolled HF (unstable HF)
Which BB’s can be used in HF?
Bisoprolol and carvediolol
What counselling advice would you give someone on a BB?
Do not stop taking abruptly without advice of your doctor
