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Drug Classes > Beta Blockers > Flashcards

Beta Blockers Flashcards

1
Q

BB block ….. which are found in the ……

A

Beta adrenoreceptors

Heart, lungs, bronchi, vessels, pancreas, liver

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2
Q

MOA of BB

A

Slow the heart and depress the myocardium

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3
Q

Which BB are more effective?
Where are B1 and B2 found?

A

Equally effective
B1 in heart
B2 in lungs

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4
Q

Intrinsic sympathomimetic activity is…

A

The BB ability to stimulate and block adrenergic receptors

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5
Q

ISAs cause …… and ……

A

Less bradycardia and less coldness of extremities

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6
Q

Examples of ISAs are….

A

ICE PACO

Pindolol
Acebutalol
Celiprolol
Oxprenolol

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7
Q

Which BB cause less nightmares and why

A

Water soluble because theyre less likely to cross the BBB

Celiprolol
Atenolol
Nadolol
Sotalol

Water CANS

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8
Q

Which BB have the least effect on beta (bronchial receptors) what does this mean?

A

Cardioselective
Less effect on airways hence better to give in well controlled asthmatics if no other alternative

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9
Q

Which BB are chosen in coexisting conditions e.g., MI, HF at a low dose

A

Cardioselective
By specialist and monitor closely

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10
Q

Examples of Cardioselective

A

MANBA

Metoprolol
Atenolol
Nebivolol
Bisoprolol
Acebutalol

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11
Q

Is sotalol a Cardioselective BB

A

No

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12
Q

Which BB are long acting. How freq are they given daily?

A

BANC

Bisoprolol
Atenolol
Nadalol
Celiprolol

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13
Q

Can BB be used in diabetics?

A

Yes but with caution (preferably cardioselective BB)

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14
Q

When can BB not be used in diabetics? Why?

A

In those with frequent episodes of hypoglycaemia because it masks its symptoms such as tachycardia

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15
Q

BB can cause …. in patients with or without diabetes

A

Hypo or hyperglycamia

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16
Q

Can BB be used in HF

A

Only stable HF it is CI in unstable HF

17
Q

Propranolol indications

A

Migraine prophylaxis
Anxiety
Thyrotoxicosis

18
Q

BB cautions

A

1st degree AV block
Diabetes
Respiratory problems- asthma, COPD

19
Q

BB can reduce the effectiveness of …..

A

Epipens because they reduce the response to adrenaline (epinephrine )

20
Q

which BB can be used in pregnancy

A

Labetolol

21
Q

BB contraindications

A

Unstable HF
2nd and 3rd degree AV block
With verapamil - can cause heart block

22
Q

BB can mask the symptoms of …..

A

Thyrotoxicosis and hypoglycaemia

23
Q

Severe interaction of BB with….

A

Verapamil —> risk of hypotension bradycardia which can lead to heart block

24
Q

SE of BB

A

alopecia
Dry eyes and rashes (reversible)
GI and visual disturbances
Sexual dysfunction
Fatigue
Thrombocytopenia

25
Q

Dry eyes and rashes can be caused by… but is it reversible?

A

BB
Yes

26
Q

Thrombocytopenia is a SE of…

A

BB

27
Q

Which BB is associated with liver damage

A

Labetalol

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