Benzylic Chemistry

Question 1

Clemmenson Reduction

Answer 1

• Replaces pi bonded O with 2H’s
• Reagents: metals (ex. Zn(Hg))

Question 2

Reduction of Aromatic Nitro

Answer 2

• Replaces NO2 (nitro) with NH2
• Reagents: 1. Fe or Zn, HCl, and 2. NaOH

Question 3

Benzylic Oxidation

Answer 3

• Replaces a C-H bond with Carboxylic Acid
• Reagents: Strong Oxidant (ex. NaCr2O7 or KMnO4)

Question 4

Diazonium Salt Reaction (“sandmeyer rxn”)

Answer 4

• Replaces a N+ triply bonded with N (N2) with a Halogen (X)
• Reagents: CuX (X can be Br, Cl, or I)