benzodiazepines

Question 1

How do Benzodiazepines work?

Answer 1

enhance the effect of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) by increasing the frequency of chloride channels.

Question 2

When are benzodiazepines used?

Answer 2

sedation
hypnotic
anxiolytic
anticonvulsant
muscle relaxant

Question 3

How long should benzodiazepines be prescribed for?

Answer 3

short period of time
2-4 weeks

Question 4

how should benzodiazepines be withdrawn?

Answer 4

steps of 1/8 every fortnight

switch patient patients to equivalent dose of diazepam if regardless of decreasing steps of 1/8 des not work

reduced dose of diazepam every 2-3weeks in steps of 2 or 2.5 mg

Question 5

how much time is required to reduce dose of benzodiazepams?

Answer 5

4 weeks to 1 year

Question 6

what are the symptoms of benzodiazepine withdrawal?

Answer 6

insomnia
irritability
anxiety
tremor
loss of appetite
tinnitus
perspiration
perceptual disturbances
seizures

Question 7

what are the symptoms of benzodiazepine withdrawal syndrome?

Answer 7

insomnia
irritability
anxiety
tremor
loss of appetite
tinnitus
perspiration
perceptual disturbances
seizures

Question 8

how long does it take to exhibit symptoms of benzodiazepine syndrome?

Answer 8

up to 3 weeks

Question 9

how long does it take to exhibit symptoms of benzodiazepine syndrome?

Answer 9

up to 3 weeks

Question 10

what is a way of remember role of benzodiazepines and barbiturates?

Answer 10

GABAA drugs
benzodiazipines increase the frequency of chloride channels
barbiturates increase the duration of chloride channel opening

Frequently Bend - During Barbeque

…or…

Barbidurates increase duration & Frendodiazepines increase frequency