Benzodiazapenes Flashcards
Diazepam (Valium)
Mechanism: bind to GABA receptors
Half-life: 20-70hr
Comments: ADDICTIVE! reduce anxiety and agitation; Metabolism: Liver; withdrawal symptoms: seizures, death
Side effects: sedation, behavioral disinhibition; psychomotor impairment; cognitive impairment; confusion; ataxia
Lorazepam (Ativan)
Mechanism: bind to GABA receptors
Half-life: 10-70hr
Comments: ADDICTIVE! reduce anxiety and agitation; Metabolism: Liver; withdrawal symptoms: seizures, death
Side effects: sedation, behavioral disinhibition; psychomotor impairment; cognitive impairment; confusion; ataxia
Clonazepam (Klonopin)
Mechanism: bind to GABA receptors
Half-life: 19-50hr
Comments: ADDICTIVE! reduce anxiety and agitation; Metabolism: Liver; withdrawal symptoms: seizures, death
Side effects: sedation, behavioral disinhibition; psychomotor impairment; cognitive impairment; confusion; ataxia
Alprazolam (Xanax)
Mechanism: bind to GABA receptors
Half-life: 8-15hr
Comments: ADDICTIVE! reduce anxiety and agitation; Metabolism: Liver; withdrawal symptoms: seizures, death
Side effects: sedation, behavioral disinhibition; psychomotor impairment; cognitive impairment; confusion; ataxia
Chlordiazepoxide (Librium)
Mechanism: bind to GABA receptors
Half-life: 24-48hr
Comments: ADDICTIVE! reduce anxiety and agitation; Metabolism: Liver; withdrawal symptoms: seizures, death
Side effects: sedation, behavioral disinhibition; psychomotor impairment; cognitive impairment; confusion; ataxia
Oxaxepam (Serax)
Mechanism: bind to GABA receptors
Half-life: 5-15hr
Comments: ADDICTIVE! reduce anxiety and agitation; Metabolism: Liver; withdrawal symptoms: seizures, death
Side effects: sedation, behavioral disinhibition; psychomotor impairment; cognitive impairment; confusion; ataxia
Temazepam (Restoril)
Mechanism: bind to GABA receptors
Half-life: 8-12hr
Comments: ADDICTIVE! reduce anxiety and agitation; Metabolism: Liver; withdrawal symptoms: seizures, death
Side effects: sedation, behavioral disinhibition; psychomotor impairment; cognitive impairment; confusion; ataxia
Midazolam (Versed)
Mechanism: bind to GABA receptors
Half-life: 1.5-3.5hr
Comments: ADDICTIVE! reduce anxiety and agitation; Metabolism: Liver; withdrawal symptoms: seizures, death
Side effects: sedation, behavioral disinhibition; psychomotor impairment; cognitive impairment; confusion; ataxia
Triazolam (Halcion)
Mechanism: bind to GABA receptors
Half-life: 1.5-5hr
Comments: ADDICTIVE! reduce anxiety and agitation; Metabolism: Liver; withdrawal symptoms: seizures, death
Side effects: sedation, behavioral disinhibition; psychomotor impairment; cognitive impairment; confusion; ataxia