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10 ways to kill a patient > Benzo OD > Flashcards

Benzo OD Flashcards

1
Q

What is the clinical picture of benzodiazepine OD?

A

confusion

  • retrograde amnesia
  • low GCS
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2
Q

Investigations in benzodiazepines OD

A

BG

  • U&E
  • FBC
  • urine toxicity -> to role out other drugs OD (the person would be unconscious so no Hx provided)
  • ECG
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3
Q

Management of benzodiazepine OD

A

Flumazenil - competitive antagonist

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4
Q

Flumazenil

  • MoA
A

Flumazenil

*antidote for benzodiazepine OD

MoA: selective GABA-A antagonist (competative inhibitor)

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5
Q

Side effects of Flumazenil

A

Side effect:

  • promote seizures (that may be resistant as we cannot treat it with benzodiazepines - due to already OD on them) - so often just ‘watch and wait’ approach
  • arrhythmias
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10 ways to kill a patient (8 decks)

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