Benign Prostatic Hyperplasia: Etiology, Pathophysiology, Epidemiology, and Natural History Flashcards
1
Q
Which statement is correct regarding the role of androgenic hormones in the etiology of benign prostatic hyperplasia (BPH)?
a. Testosterone and dihydrotestosterone (DHT) are the sole causes of the hyperplasia taking place in the prostate after the age of 40 years.
b. The total amount of androgen receptors in the prostate decreases with aging, leading to a lesser response to androgenic stimuli.
c. DHT is considered the more potent of the androgenic steroid hormones by a factor of approximately 10:1.
d. Of the two 5α-reductase isoforms, type 1 is most commonly found in the prostate.
e. Only testosterone produced in the testis and not in the adrenal gland enters into the prostate gland.
A
