Benign neoplasms and reactive lesions Flashcards
Oral diseases affecting epithelium (6)
Reactive: mucoceles
Infective: focal epithelial hyperplasia, verruca vulgaris, papilloma
Neoplastic: squamous cell carcinoma, salivary gland tumours
Oral diseases affecting fibrous tissue (5)
Congenital/ developmental: gingival fibromatosis
Inflammatory: gingival hyperplasia
Reactive: pyogenic granuloma, fibrous hyperplasia, giant cell granuloma
Neoplastic: fibroma
Oral diseases affecting blood vessels (3)
Congenital/ developmental: haemangioma, lymphangioma
Neoplastic: angiosarcoma
Oral diseases affecting fat (1)
Neoplastic: lipoma
Oral diseases affecting nerves (4)
Reactive: traumatic neuoma
Neoplastic: neurofibroma, neurilemmona
Idiopathic: granular cell tumour
Oral diseases affecting muscle (3)
Neoplastic: rabdomyoma, leiomyoma, sarcomas
What is an epulis? (1)
A gingival swelling
Examples of localised epulides (5)
Fibrous hyperplasia (fibro-epithelial polyp) Pyogenic granuloma Peripheral giant cell granuloma Gingival cysts Bohns nodules
Examples of generalised swellings of gingival tissue (6)
Chronic hyperplastic gingivitis Leukaemic infiltration Endocrine related (puberty, pregnancy) Crohn's disease Gingival fibromatosis Drug induced hyperplasia
Clinical features of fibrous epulis (fibrous hyperplasia) (5)
Pedunculated or sessile Same colour as normal mucosa Firm Painless unless traumatised Caused by trauma: dentures, teeth orthodontic appliances
Fibrous hyperplasia: histological appearance (2)
Overgrowth of fibrous CT
Covered by hyperkeratinised stratified squamous epithelium
Management of fibrous hyperplasia (3)
Excision
Remove cause
Send for histopathological examination
Features of a pyogenic granuloma (6)
- clinical
- who if affects
Red/ blue/ purple vascular growth Sessile or pedunculated Rapid growth Soft, bleeds easily Usually <40yrs Common in pregnancy/ puberty (pregnancy epulis)
Causes of pyogenic granuloma (2)
Caused by trauma e.g. plaque, calculus, denture, orthodontic appliance
In pregnancy/ puberty hormonal induced exuberant repsonse to above
Pyogenic granuloma: histological appearance (2)
Overgrowth of very vascular granulation tissue (endothelial cells and fibroblasts)
Explains red colour seen clinically
Management of pyogenic granuloma (4)
Excision and remove cause
If patient is pregnant, improve oral hygiene and excise but may recur
Lesions may mature into dense fibrous tissue (fibrous epulis)
Also found at other sites in oral mucosa
Peripheral giant cell granuloma features (6)
Soft red/ blue sessile or pedunculated swelling
Usually anterior teeth, mandible > maxilla
Average <40yrs
Similar to pyogenic granuloma clinically
May cause superficial bone resorption
Only found on gingiva
Peripheral giant cell granuloma (5)
Vascular fibrous tissue
Numerous multinucleate giant cells
Haemorrhage
Histological diagnosis: giant cell lesion
-same as those arising in bone histologically e.g. central giant cell granuloma and hyperparathyroidism
Management of peripheral giant cell granuloma (3)
Determine whether lesions has arisen on gingiva or within bone and burst through cortical plate - rads
If arisen in bone differential diagnosis includes central giant cell granuloma and hyperparathyroidism
Excision
-curettage of underlying bone to prevent recurrence
-send for histopathological examination
Differential diagnosis of epulides (4)
Firm, mucosa coloured: fibrous epulis
Soft, red, red/ blue: pyogenic granuloma, giant cell granuloma
Pregnant/ puberty more likely pyogenic granuloma
Definitive diagnosis by excisional biopsy
EXCLUDE ABSCESS from tooth or gum: red/ yellow/ soft/ fluctuant
Hereditary generalised gingival swellings (1)
Gingival fibromatosis
Inflammatory generalised gingival swellings (1)
Chronic hyperplastic gingivitis