Benign Disease Flashcards

1
Q

Features of a fibroadenoma?

A
Young 
Smooth, firm, highly mobile mass
Painless 
Slow growing 
"Breast mouse"
Often regress after menopause
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2
Q

Presentation of a breast cyst?

A
  • 30-50 years
  • Smooth, mobile lump, well-circumscribed (similar to fibroadenoma)
  • PAIN possible - worse before menstruation
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3
Q

Presentation of Intraductal carcinoma

A

35-55 years
Blood-stained nipple discharge
Not usually palpable mass/mammography
Tender or pain

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4
Q

What is mastitis?

A

Inflammation of the breast tissue (infectious or non-infectious)

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5
Q

Presentation of mastitis?

A

Tenderness
Redness
Swelling
Systemic - fever, malaise

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6
Q

What is fat necrosis?

A

An inflammatory reaction to adipose tissue damage.

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7
Q

Diagnosis of intraductal papilloma

A

Triple assessment:

(1) Clinical assessment - history/exam
(2) Imaging (US, mammography + MRI)
(3) Histology (core biopsy OR vacuum-assisted biopsy)

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8
Q

What will an intraductal carcinoma show on a mammogram?

A

A filling effect - an area that doesn’t fill with constrast

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9
Q

Management of intraductal carcinoma?

A

Complete surgical excision –> examine for atypical hyperplasia or cancer

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10
Q

How are mammogram images of a lump graded?

A
M1 - normal
M2 - benign 
M3 - probably benign
M4 - probably malignant
M5 - malignant
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11
Q

Presentation of fat necrosis?

A

Painless, firm, irregular breast mass
Fixed
Skin thickening/dimpling
Possible nipple inversion

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12
Q

Causes of fat necrosis?

A

Trauma, radiotherapy or surgery

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13
Q

What’s fibrocystic breast changes?

A

Tissue, ducts and lobules become fibrotic and cystic.

Occur within 10d prior to menstruation and resolves after menopause

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14
Q

Features of fibrocystic disease?

A

Different areas, usually bilateral:

  • lumpiness
  • breast pain or tender (mastitis)
  • Fluctuation of breast size
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15
Q

Management of fibrocystic breast disease?

A

(1) Exclude cancer
(2) Manage cyclical breast pain w/:
- support bra
- NSAIDs
- avoid caffiene
- apply heat to area
- Hromonal - danazol/tamoxifen under specialist guidance

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16
Q

Management of breast cyst?

A

Rule out cancer (imaging, potential aspiration/excision)

17
Q

Why might we require histology after investigating fat necrosis with an US or mammogram?

A

Fat necrosis has similar appearance to cancer –> perform fine needle aspiration + core biopsy

18
Q

What’s a lipoma?

A

Benign tumour of adipose tissue

19
Q

Features of a lipoma?

A
  • soft
  • painless
  • mobile
  • no skin changes
20
Q

What is a galactocele?

A

Break milk filled cysts - lactiferous duct becomes blocked commonly during breast feeding

21
Q

Features of galactocele?

A
  • firm
  • mobile
  • painless lump beneath areola
22
Q

What’s a phyllodes tumour?

A

Rare tumour of stroma of breast occuring between 40-50. Can be benign, borderline or malignant

23
Q

Treatment of phyllodes tumour?

A
Surgical excision (wide excision).
Chemo if malignant or mets