Benign D/O of Breast & Genital tract Flashcards

1
Q

What is a fibroadenoma composed of

A

glandular / cystic epithelial structures surrounded by cellular stroma

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2
Q

Most common breasr mass ID’d in adolescent female

A

Fibroadenoma

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3
Q

what is considered “Fibrocystic changes” to breast tissue

A

palpably nodular breast tissue

histologic pattern dilated ducts / acini invested w/ dense collagenous stroma

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4
Q

Are “Fibrocystic changes” to breast tissue by themselves considered a cancer risk?

A

No

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5
Q

How is fibrocystic breast disease characterized by

A

Hyperplasia; multi bilat cysts w/pain & tenderness (greater Sx in premenstrual)

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6
Q

how to decrease Sx in fibrocystic breast disease

A

decrease chocolate
+/- caffine
wear support bra
avoid breast trauma

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7
Q

what is a green breast discharge r/t

A

content of cholesterol dieposides

not infx / malignancy

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8
Q

What type of breast discharge must be evaluated

A

spontaneous discharge

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9
Q

How do Pt’s present with mastitis in the Puerperal setting (during child birth/ immediately after)

A

warm / tender / diffuse breast erythema

+/- fever / malaise /myalgias / leukocytosis

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10
Q

MC organism of mastitis

A

staphylococcus

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11
Q

those breast feeding w/ mastitis, can they continue to breast feed?

A

yes

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12
Q

If mastitis does not improve after ABX what should be done?

A

US to r/o abcess

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13
Q

what should be done w/ those that develop mastitis in Nonpuerperal setting (not during child birth/ immediately after)

A

Image / biopsy to exclude inflammatory breast cancer;

Uncommon

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14
Q

If a Nonpuerperal Pt has a peripheral breast abscess what are the usual causes

A

infx from folliculitis / EIC / Montgomery gland

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15
Q

Tx of peripheral breast abscess

A

I&D & ABX

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16
Q

If a Nonpuerperal Pt has a Subareolar breast abscess what are the usual causes

A

keratin-plugged mild ducts

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17
Q

Tx of subareolar breast abscess

A

duct excision & removal of sinus tracts

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18
Q

Mastalagia is ___, and seen more in women ____

A

breast pain; women nearing menopause

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19
Q

breast pain that is bilat, diffuse, most severe during late luteal phase is ____, and requires ____

A

Cyclic;

no specific eval needed, Tx Sx

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20
Q

Breasr pain that is focal & no relation to menstral cycle is ____, & could be ____or ___

A

Noncyclic, frequently simple cyst, could be Cancer

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21
Q

this vulvar Dx presents classically in post-menopausal women w/inflamed dermis

A

Lichen Sclerosis

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22
Q

What are the Sx’s of Lichen Sclerosis

A

Early: pruritus, irritation, vulvar thickening
Late: burning & dyspareunia, introital stenosis

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23
Q

how does Lichen Sclerosis on the vulva appear as

A

cellophane paper
tissue paper
crinckled cigarette paper

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24
Q

Tx of Lichen Sclerosis

A
Sx Tx;
min chem/mech irritation
topical steroid (Clobestasol)
Retinoids for severe/unremitting Sx
Phototherapy/5aminolevulinic acid for severe Sx
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25
Q

This results from an intense itch/scratch cycle and has non-neoplastic morphologic alteration of vulvar skin

A

Lichen simplex chronicus

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26
Q

MC site and early findings of Lichen Simplex Chronicus

A

Labia Majora;

excoriations w/background erythema

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27
Q

Tx of Lichen Simplex Chronicus

A
Eliminate Triggers
Lube affected area
Sitz baths
oral antihistamines
wear cotton gloves @ night
Topical steroids
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28
Q

If Lichen Simplex Chronicus id not resolved in 1-3 wks?

A

biopsy

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29
Q

this is uncommon autoimmune d/o of T-cells/ Rx induced (NSAIDS, B-blockers) involves cutaneous & mucosal surfaces

A

Lichen Planus

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30
Q

Pts w/ lichen planus complain of

A

chronic vaginal discharge w/ intense vulvovaginal pruritis, burning pain, dyspareunia & postcoital bleeding

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31
Q

what are the 3 variants of lichen planus

A

Erosive (MC & most difficult)
Papulosquamous
Hypertrophic

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32
Q

description of lichen planus

A
purple
pruritic
polygonal
papules
plaques
33
Q

Tx of Lichen Planus

A

Topical: Clobetasol

Vaginal hydrocortisone supp.

34
Q

this occurs in skin folds from friction between moist skin w/signs/Sx of burning / itching hyperpigmentation

A

Intertrigo

35
Q

Tx of Intertrigo

A
Drying agents (corn starch, etc.)
Inflammation: mild top steroids
Infx: Tx cause
weight loss
light-weight loose clothing
36
Q

what is the MCC of vaginal irritation after menopause

A

Atrophic Vaginitis

37
Q

Signs/Sx of Atrophic Vaginitis

A

vulvar irritation
clear/yellow/blood tinged discharge
urinary Sx
Dyspareunia

38
Q

diagnosis of atrophic vaginitis

A

friable vaginal epithelium
los of rugae
pale mucosa
pap smear changes

39
Q

Tx of Atrophic Vaginitis

A

Topical estrogen

Tx concomitant Infx

40
Q

This cyst occurs in duct w/ NO PAIN / common in reproductive age women

A

Bartholin Cyst

41
Q

A Bartholin Cyst in a women > 40 is

A

concerning for Cancer; refer for Bx

42
Q

Tx of Bartholin Cyst

A

None if Asymptomatic; I&D alone discouraged

Word Cath for both cyst & abscess
Marsupialization (if Failed Word)

43
Q

A Bartholins Abscess is associated with what bug

A

polymicrobial but correlates w/ gonorrhea/chlamydia

44
Q

Sx of Bartholins Abscess

A

Severe pain
Difficulty walking / sitting
dyspareunia

45
Q

Tx of Bartholins Abscess

A

fluctuant I&D for relief & placement of Word Cath

ABX if recurrent or High risk for complicated infection

46
Q

WHo are at high risk of complicated infx with Bartholins abscess

A

Pregnant
cellulitis
systemic infection
immunosuppressed

47
Q

what ABX should be used for thoe at high risk of complicated infection w/ bartholins abscess

A

Augmentin 875mg 2x daily + Clindamycin 300mg 4x daily x 1 week

48
Q

Cervical stenosis is characterized by

A

contraction of scar tissue / adhesions w/in endocervical canal blocks os

49
Q

Sx of Cervical Stenosis

A

dysmenorrhea
amenorrhea
infertility

50
Q

Tx of cervical stenosis

A

cervical dilators

vaginal estrogens x 4 wks in hypoestrogenic women (post-menopausal)

51
Q

“trapped” Columnar cells beneath squamous cells during metaplasia continue to secrete mucus = descrete cyst
(smooth clear white/yellow rounded elevations)

A

Nabothian Cyst

52
Q

Nabothian Cysts are usually

A

asymptomatic w/ no Tx needed

53
Q

these may have leucorrhea / postcoital spotting, arise in endocervical canal in reproductive yrs; typically < 3cm

A

Cervical Polyp

54
Q

Tx of Cervical Polyp depends on

A

size (Tx large, symptomatic, or atypical)

55
Q

Tx of small pedunculated cervical polyp

A

grasp @ base w/ forcep & twist

56
Q

Tx of sessile cervical polyp

A

remove w/ Bx forceps, cauterize base

57
Q

what are the estrogen dependent uterine D/O

A

Leiomyomata “Fibroids”
Adenomyosis
Endometrial hyperplasia

58
Q

what is the MC pelvic tumor in women

A

Leiomyomata “Fibroids”

59
Q

Types of Leiomyomata “Fibroids”

A

Intramural
Submucosal
Subserosal

60
Q

Sx of Leiomyomata “Fibroids”

A
most asymptomatic
bleeding
mass effect; pressure, urinary freq, incontinence, constipation
Pelvic Pain
Infertility
61
Q

Preferred method to diagnose Leiomyomata “Fibroids”

A

Ultrasound

62
Q

Nests of endometrial glands & stroma embedded w/in muscular uterine wall

A

Adenomyosis

63
Q

adenomyosis presents as

A

heavy abnormal uterine bleeding /dysmenorrhea in parous women ages 40-50

64
Q

Tx of adenomyosis

A

Classic: hysterectomy

Medical: GnRH agonist, Danazol
Progestins (Mirena)

65
Q

when is a ovarian cyst considered functional

A

> 3cm

66
Q

Premenopausal womanw/ =5cm simple/hemorrhagic ovarian cyst. what do you do to eval?

A

no additional Tx required

67
Q

Premenopausal womanw/ >5cm but <7cm simple/hemorrhagic ovarian cyst. what do you do to eval?

A

TVS (TVUS?) repeat in 6-12wks; if persistent TVS yearly

68
Q

Premenopausal womanw/ >7cm simple/hemorrhagic ovarian cyst. what do you do to eval?

A

MRI or surgical eval

69
Q

Post-menopausal woman with =1cm simple ovarian cyst what is needed

A

nothing; normal finding

70
Q

Post-menopausal woman with =5cm simple ovarian cyst what is needed

A

CA125 level –> normal –> TVS (TVUS?) repeated in 6-12wks–> if persistent TVS yearly

71
Q

Post-menopausal woman with >7cm simple ovarian cyst what is needed

A

MRI or surgical consult

72
Q

In premenopausal woman w/ indeterminate/probably benign cyst (hemorrhagic, matureteratoma, andometrioma) what should be done?

A

TVS repeated @ 6-12wks if persistent –> consider MRI / surgical consult

73
Q

Ovarian cyst with qualities suggesting malignancy appear as and need?

A

Thick (>3mm) irregular septations
Nodule w/blood flow

consider surgical eval

74
Q

50-80% of ovarian torsion cases have what?

A

ovarian mass

75
Q

What increases the risk of ovarian torsion & what has the highest rates for torsion

A

1) ovaries >6cm

2) adnexa 6-10cm

76
Q

Which adnexa is more commonly affected by torsion

A

Right, b/c left mobility limited r/t sigmoid colon

77
Q

Female Pt presents w/ sudden onset sharp lower ABD pain that is worse over several hours & radiates to flank / groin / thigh (may have low grade fever which suggest what is this

A

1) Ovarian Torsion

2) Necrosis

78
Q

Tx of ovarian torsion

A

Salvage as possible
resect tumor/cyst
possible oophoropexy
w/ necrosis/rupture w/hemorrhage –> removal of adnexal structures