Benign Bone Tumours

Question 1

What are 3 examples of benign primary bone tumours?

Answer 1

Osteid osteoma

Endochondroma

Giant cell tumour of bones

Question 2

What is an osteoid osteoma?
Who does it typical affect?
How might someone present?

Answer 2

Tumour which forms due to increased osteoid production leading to lesions in the long bones of body

Children (M:F 2:1)

Nocturnal pain relieved by NSAIDs

Question 3

What is an enchondroma?
Who does it typically effect?
Where does it normally effect?
How is it treated?

Answer 3

Benign cartilagenous tumour

20-49

Small joints of hands and feet

Excision

Question 4

What is giant cell tumour of bone? 
Who does it primarily effect?
Where does it affect?
How does it present? 
How can it be managed?

Answer 4

Locally aggressive neoplasm formed from neoplastic ovoid mononuclear cells interspaced with large osteoclast-like giant cells

20-45 yo

Effect end of long bones (epiphyseal)

Bones pain
Swelling
Restricted joint movement
Pathological fractures

Denosumab
-blocks osteoclast activity to prevent osteolytic part of tumour manifestation